| Objective: By comparing heat-sensitive acupoint ginger-separated moxibustion with trimebutine maleate in treating IBS-D with spleen-kidney yang deficiency,this study explores the clinical efficacy and safety of heat-sensitive acupoint ginger-separated moxibustion in treating IBS-D with spleen-kidney yang deficiency,so as to provide a new treatment idea for this disease.Method: 72 patients with IBS-D spleen-kidney yang deficiency who are treated in anorectal clinic of Changchun University of TCM were randomly divided into 2 groups(the treatment group and the control group).Each group had 36 cases.The treatment group was treated with heat-sensitive acupoint ginger moxibustion,once a day,5 times a week,while the other one was given trimebutine maleate tablets to take orally,0.1g each time,3times a day.Both groups were continuously treated for 4 weeks.We respectively counted the scores of IBS TCM Syndrome Scale and Hamilton Depression Scale(HAMD)before and after the treatment,and the data was analyzed by spss25.0,so as to evaluate the relief degree of clinical symptoms and the improvement of mental mood.Results:1.Compared with the scores before receiving treatment,the scores of IBS TCM syndrome scale and HAMD scale in both groups were significantly lower(p<0.05),which proved that both treatments could significantly improve the clinical symptoms and depression of IBS-D patients with spleen and kidney yang deficiency.2.The improvement of the total score of TCM syndromes in the treatment group is better than another one(P<0.05),indicating that compared with the control group,the overall therapeutic effect of the treatment group is better;In terms of single score,the scores of abdominal distension,soreness of waist and knees and cold limbs in the treatment group were significantly lower(P<0.05),which indicated that the clinical efficacy of the treatment group was better than another one in improving these three syndromes,but there was no significant difference in diarrhea,abdominal pain and anorexia between the 2 groups(P>0.05),which indicated that the two groups had the same therapeutic effects on diarrhea,abdominal pain and anorexia.3.The score of HAMD scale in the treatment group was significantly lower than another group(P<0.05),indicating that the treatment group has more advantages in improving depression.4.Comparing the overall curative effect of the 2 groups,the total effective rate of the treatment group is 91.18%,while the control group is 82.86%,indicating that the curative effect of the treatment group is significantly better than the other one(P<0.05).Conclusion:1.Heat-sensitive acupoint ginger-separated moxibustion and oral administration of trimebutine maleate can both effectively treat IBS-D with spleen-kidney yang deficiency,improve depression,and have good safety.2.Compared with the trimebutine maleate,heat-sensitive acupoint ginger-separated moxibustion has better overall curative effect,and it has more advantages in improving abdominal distension,soreness of waist and knees,cold limbs and depression,which is worthy of clinical promotion. |