Diagnosis Of Pathological Types Of Malignant Lung Tumors By Dual-layer Detector Spectral CT

Objectives:By retrospectively analyzing the energy spectrum of squamous cell carcinoma,adenocarcinoma,small cell lung cancer(SCLC),and pulmonary metastases that underwent dual-layer detector spectral CT(DLCT)3-phaze scan of the chest,we explored the value of multi-parameter energy spectrum in the assessment of pathological types of lung tumors.Methods:Cases of squamous cell carcinoma(n=20),adenocarcinoma(n=24),SCLC(n=26),and metastases(n=14)were collected.Then the largest cross-sectional area of the lesion(LCA),CT values in the plain scan phase,arterial and venous phases(HU,HUa,HUv),iodine 1concentration and effective atomic number in the arterial and venous phases(ICa,ICv,1Zeff(a),Zeff(v))were measured and compared among the non-small cell lung cancer(NSCLC),SCLC and metastases,and other three groups of SCLC,squamous cell carcinoma and adenocarcinoma.Results:Only the LCA is statistically different among SCLC,NSCLC and metastases(P<0.05).And the treated subgroup analysis did not show significant difference among the groups.However,the untreated subgroup analysis showed that there was a significant difference between NSCLC and metastases in LCA,SCLC and metastases in ICa,NSCLC and SCLC in HUv,NSCLC and SCLC in Zeff(v)(P<0.05).Conclusion:The energy spectrum parameters of DLCT have a certain clinical value in distinguishing untreated NSCLC from SCLC in the Zeff(v)and distinguishing untreated SCLC from metastases in the ICa.