Fear Of Disease Progression In Lymphoma Patients And Its Influencing Factors

Objective:To investigate the fear of disease progression in lymphoma patients.And analyze its influencing factors.Methods:General information questionnaire,Psychological Resilience Scale(CD-RISC),Insomnia Severity Index(ISI),Generalized Anxiety Disorder 7-item Scale(GAD-7),patient health questionnaire Depression Scale were used(PHQ-9),Quality of Life(QOL-C30)and Simplified Fear of Disease Progression Scale(Fo P-Q-SF)were used to investigate the psychological status of 106 patients with lymphoma.Logistic regression was used to analyze the related factors affecting the patients’ fear of disease progression.Results:A total of 106 questionnaires were sent out,and 103 were effectively received with a recovery rate of 97%.The average score of the simplified fear of disease progression scale was(29.39±9.5)points,including the social and family dimension(14.01±4.84)points and the physical health dimension(15.38±5.34)points.A total of 34 patients scored higher than 34 points on the simplified fear of disease progression scale,accounting for 33.01%(34/103).The highest score was(2.93±1.3).In high level fear group,women and course of disease > 9 months and III-IV pathological stage composition ratio were higher than normal group(P<0.05);FoP-Q-SF score waspositively correlated with ISI score,GAD-7score and PHQ-9 score(P<0.05),were negatively correlated with CD-RISC score and QLQ-C30 score(P<0.05);ISI score was positively correlated with GAD-7 score and PHQ-9 score(P<0.05),was negatively correlated with QLQ-C30 score(P<0.05);CD-RISC score was positively correlated with QLQ-C30 score(P<0.05),were negatively correlated with GAD-7 score and PHQ-9 score(P<0.05);GAD-7 scores were positively correlated with PHQ-9 scores(P<0.05),was negatively correlated with QLQ-C30 score(P<0.05),PHQ-9 score was negatively correlated with QLQ-C30 score(P<0.05);Logistic multivariate regression analysis showed: female,course of disease>9 months,ISI score,CD-RISC score,Gad-7 score and PHQ-9 score were all independent risk factors for lymphoma patients’ fear of disease progression(P<0.05);The scores of physical function,role function,emotional function,cognitive function,social function and overall quality of life in the high level fear group were all lower than those in the normal group(P<0.05),the scores of fatigue,pain,dyspnea,insomnia,diarrhea and economic hardship in the high level fear group were higher than those in the normal group(P<0.05).Conclusions:Fear of disease progression in lymphoma patients seriously affects quality of life,femininity and disease course>9 months,ISI score,CD-RISC score,GAD-7 score and PHQ-9 score are all independent risk factors affecting the fear of disease progression in lymphoma patients,and prevention and control should be strengthened.