| Objective: To observe the clinical efficacy and safety of acupotomy combined with medicine in the treatment of rheumatoid arthritis button deformity liver and kidney insufficiency syndrome to provide scientific basis for clinical treatment of the disease.Methods: Sixty patients who met the inclusion criteria in Chongqing Dijiang Hospital of Traditional Chinese Medicine were selected and divided into control group and treatment group,with a sample size of 30 patients in each group.The treatment plan of control group was basic traditional Chinese and Western medicine treatment,including celecoxib capsule,Leflumide tablet,methotrexate tablet and Duhuazi Decoction.The treatment group was additionally treated with acupotomy once a week for 4 weeks as a course of treatment.Full course of treatment,were recorded before and after treatment in patients with observation index,the evaluation of joint symptoms related to patients with tenderness score(VAS score and joints,joint swelling,score),joint mobility,grip strength,joint activity function score,laboratory indexes(CRP,ESR,RF),TCM syndrome integral,carried out a statistical analysis on the safety index,To evaluate the clinical efficacy and safety of acupotomy combined with drug administration in the treatment of rheumatoid arthritis button deformity.Results:(1)Joint symptom related evaluation: VAS score,joint tenderness score and joint swelling score were compared between the two groups before and after treatment,and P value was >0.05,showing no significant statistical significance,indicating comparability.Intra-group comparison between the two groups before and after treatment,P<0.05,was statistically significant,indicating that both the control group and the treatment group had significant efficacy in the improvement of joint symptoms,and inter-group comparison after treatment,P<0.05,was statistically significant,indicating that the treatment group in the control group was superior to the control group.(2)Joint function related evaluation: The evaluation results of range of motion,grip strength and joint mobility were compared between the treatment group and the control group before and after treatment,and there was no significant statistical difference between the two groups before treatment(P<0.05).In the control group,there was no significant improvement in the range of motion and the evaluation of joint mobility(P>0.05),while the improvement of grip strength was statistically significant(P <0.05).In the treatment group,the range of motion,grip strength and joint mobility were statistically analyzed before and after treatment,P < 0.05,indicating statistical significance.After treatment,the comparison between the two groups showed P <0.05,indicating that the difference in treatment results between the two groups was statistically significant.(3)Laboratory indicators: CRP,ESR and RF results were statistically analyzed between the treatment group and the control group before and after treatment.There was no significant difference between the two groups before treatment(P>0.05),indicating comparability.Intra-group comparison between the two groups after treatment and before treatment,P<0.05,treatment can improve laboratory indicators in both groups;And the comparison of the results between the treatment group and the control group after treatment,P<0.05,indicating statistical significance,indicating that the treatment group is superior to the control group.(4)Comparison of TCM syndrome score: THE comparison of TCM syndrome score between the two groups before treatment,P>0.05,showed no significant difference;After treatment,the comparison between the two groups,P<0.05,statistically significant,both groups can improve TCM syndrome;The comparison between the treatment group and the control group showed that the treatment group was superior to the control group,P<0.05.(5)Comparison of range of motion: the two groups were comparable before treatment,P>0.05.After treatment,the comparison between the experimental group and the control group,P<0.05,the difference is significant,and the treatment group is better than the control group.The shorter the course of disease,the more obvious the improvement of range of motion,the better the treatment effect.(6)Comparison of comprehensive efficacy: after treatment,the efficacy evaluation of the two groups was as follows: the total effective rate of the control group was 83.3%;The total effective rate of the treatment group was 90%.The two groups were compared between the two groups,and the mann-Whitney U rank-sum test of two independent samples showed that P<0.05,indicating that the therapeutic effect of the two groups was statistically significant,indicating that the therapeutic effect of the treatment group was better than the control group.Conclusion: Needle knife combined with traditional Chinese and western medicine treatment of rheumatoid arthritis(RA)take orally buttons abnormalities in patients with liver and kidney deficiency type pattern,can alleviate the symptoms of joint pain,joint swelling,tenderness,and improve the ability of motion,grip strength,joint activities,and the needle knife therapy curative effect is better than just use traditional Chinese and western medicine internal use,that needle knife therapy in patients with liver and kidney deficiency type rheumatoid arthritis clinical curative effect is reliable,Worthy of clinical application. |
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