Analysis Of Clinical Characteristics Of Primary Liver Cancer And Related Factors Of TCM Syndrome Type

Purpose:To explore the distribution law of TCM syndrome types of patients with primary liver cancer and the correlation between TCM Syndrome Types and laboratory indicators,so as to provide supplement and reference for clinical dialectics of patients with primary liver cancer,and evaluate its diagnostic value for TCM syndrome types.Material and method: Retrospective analysis was used to collect and sort out the medical records of patients with primary liver cancer who were treated in the tumor ward of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from September 2018 to September 2020.Gender,age,general condition,personal history,symptoms,signs,blood routine,hepatitis B(HBV),total bilirubin(TBIL),albumin(ALB),alanine aminotransferase(ALT),aspartate aminotransferase(AST),ascites,hepatic encephalopathy,liver cirrhosis and other information to establish a database,import it into SPSS26.0 statistical analysis software,use normal distribution test,chi-square test,rank sum test and other test methods to seek statistical analysis between data The factors that have judgment value with TCM syndrome types in patients with primary liver cancer were screened out,and P<0.05 was statistically significant.Results:1.Accordingtotheinclusionandexclusioncriteria,therewere75 patientswithprimarylivercancerint hisretrospectivestudy,including55malepatientsand20 femalepatients,theoldestagewas89yearsol d,theyoungestagewas38 yearsold,andtheaverageagewas63.05±10.02 yearsold,theaverageageofo nsetinfemalepatientswas62.23±10.02 yearsold,andtheaverageageofonsetinmalepatientswas63.72±11.33 yearsold,andtheageofonsetinmalepatientswashigherthanthatinfemalepatients.Thedistributionof TCMsyndrometypesin.2.75patientswithlivercancer;liverdepressionandspleendeficiencysyndrome(28cases,accounting for37.33%),livergallbladderdamp-heatsyndrome(23cases,accountingfor30.66%),liverdepressi onandqistagnationsyndrome(9cases,accountingfor12%),liver-kidneyyindeficiencysyndrome(8cases,accountingfor10.66%),qistagnationandbloodstasissyndrome(7cases,accountingfor9.33%).3.Thecommonclinicalsymptomsaredistributedasfollows:68casesofliverpain(accountingfor81.3%),56casesoffatigue(accountingfor72.1%),49casesofanorexia(accountingfor65.3%),and41 case sofabdominaldistension(accountingfor54.7%)39cases(51.3%)ofpoorsleepsoundness,38 casesof yellowbodyandeyes(51.2%),36casesofexpectoration(51.0%),35casesofweightloss(50.8%),and24casesofnausea(30.3%),22casesofvomiting(30.0%),20casesofconstipation(28.4%),19 casesof cough(27.6%),19casesoflessurination(26.2%),17casesofdizziness(23.2%),and16casesoffever(22.3%),16 casesof Shantaixi(22.2%),16casesofflankpain22.1%),15casesofirritability(22.0%),15casesofabdominalpain(22.0%),14casesofbitternessinthemouthcases(21.8%),14 casesofdrymout h(21.8%),13casesofcoldlimbs(21.1%),12casesoflowerextremityedema(20.6%),and12 casesofhi ccups(20.0%).4.Commonclinicalcomplications:33casesofascites(44%),16casesofsplenomegaly(21.33%),13 c asesofanemia(17.33%),6casesofinfection(8%),hypoalbuminemia6cases(8%)ofgastrointestinal hemorrhage,5casesofgastrointestinalbleeding(6.67%),4casesofportalhypertension(5.33%),and4casesofhepaticencephalopathy(5.33%).5.Child-Pughclassificationofliverfunction:35casesofgrade A(accountingfor46.66%),26 casesof grade B(accountingfor34.66%);and14casesofgrade C(accountingfor18.66%).Therewasnosignifi cantcorrelationbetweenthe Child-Pughclassificationofliverfunctionin TCMsyndromes,andthe Pv aluewas0.082(P>0.05).6.Causesofpathogenesis:Hepatitis Bdiseaseiscloselyrelatedtolivercancer.Thedistributionofsynd rometypesofhepatitis Bviruspatientsismainlycharacterizedbyliverandgallbladderdamp-heatsyn drome,whilethosewithouthepatitis Baremainlycharacterizedbyliverstagnationandspleendeficien cysyndrome.Hepatitis Bwasstatisticallysignificant(P<0.05).7.Therewasnostatisticalrelationshipbetween TCMsyndrometypeandpatient’sage,gender,compli cationandoperationhistory(P>0.05).8.TCMsyndrometypesandlaboratoryindicators:Therearecorrelationsbetween TCMsyndrometyp esand WBC,RBC,PT,FBG,ALB,TBIL,DBIL,ASTand ALT(P<0.05).Conclusion:1.The distribution of TCM syndrome types in this study is liver stagnation and spleen deficiency syndrome > liver gallbladder damp-heat syndrome > liver stagnation and qi stagnation syndrome > liver and kidney yin deficiency syndrome > qi stagnation and blood stasis syndrome.There is a correlation between TCM syndrome types and age,and the age of onset of liver-kidney yin deficiency syndrome is the highest.2.In this study,the male-female incidence ratio of liver cancer is 2.75:1,which is similar to the clinical reports,and the incidence increases with age.40% of liver cancer patients are related to hepatitis B virus,which means that hepatitis B virus is the cause of liver cancer.risk factors.3.Laboratory examination: The results of laboratory indexes such as WBC,PT and AST for liver and gallbladder damp-heat syndrome were significantly higher than those of other syndromes;the ALB results of liver-kidney yin deficiency syndrome were significantly lower than those of other syndromes.4.The distribution characteristics of HBV patients are mainly liver and gallbladder damp-heat syndrome,while those without hepatitis B mainly have liver stagnation and spleen deficiency syndrome.