| Objectives:This study investigated the demographic data,basic diseases,traditional Chinese medicine diagnosis information,carotid artery elasticity,laboratory indicators,and other aspects of stroke risk groups,and summarized the clinical characteristics of the risk groups;By comparing the differences between high-risk and low-risk populations in stroke,this study aims to explore the characteristics of traditional Chinese medicine(TCM)syndromes,vascular elasticity,and other factors in high-risk populations,providing reference for stroke prevention,identification,and intervention of high-risk populations in stroke.Methods:1.This study adopts a cross-sectional study method,with stroke risk population as the research object.A total of 245 subjects were included,and their general information,traditional Chinese medicine diagnosis information,and carotid artery elasticity indicators were collected to summarize the clinical characteristics of the risk population.2.By using the improved Framingham Stroke Risk Rating Scale,the subjects were divided into 120 patients with medium to high risk of stroke and 125 patients with low risk of stroke.Factor analysis and cluster analysis were used to identify the characteristics of traditional Chinese medicine syndromes in the two groups,and a comparative analysis was conducted on the general situation,traditional Chinese medicine syndrome characteristics,laboratory indicators,vascular elasticity,and other aspects of the two groups with different risk levels.The clinical characteristics of the medium to high risk population were summarized.And explore the relationship between traditional Chinese medicine syndromes,risk levels,and vascular elasticity among stroke risk groups.Results:1.The general situation of stroke risk groups shows that in terms of body size,the total proportion of overweight and obesity among stroke risk groups is as high as 66.14%.In terms of basic diseases,245 patients with hypertension and 78 patients with diabetes were included in this study,accounting for 31.8%of the total number;156 people suffer from hyperlipidemia,accounting for 63.7%of the total number;57 people suffer from coronary heart disease,accounting for 23.7%of the total number;18 people suffer from arrhythmia,accounting for 7.3%of the total number of people;41 people suffered from Hyperuricemia,accounting for 16.7%of the total;28 people suffered from Hyperhomocysteinemia,accounting for 11.4%of the total.Family history is dominated by hypertension,coronary heart disease and stroke.There are 121 patients with family history of hypertension,53 patients with coronary heart disease,38 patients with stroke,29 patients with diabetes,7 patients with hyperlipidemia and 0 patients with atrial fibrillation.Among the stroke risk population,27.3%had a history of smoking,25.7%had a history of drinking alcohol,54 had a preference for fatty,sweet,and thick flavors in their dietary habits,accounting for 25.5%,44 had a salty diet,accounting for 20.8%,and 46 drank tea frequently,accounting for 21.7%.Among the stroke risk population,56 patients remained sedentary for a long time,and 137 patients(70.9%)had a habit of exercising.Among 137 patients with exercise habits,25.5%had exercise duration less than 30 minutes,43.1%had exercise duration between 30 and 60 minutes,and 31.4%had exercise duration greater than 60 minutes.85.4%of patients mainly engage in low intensity exercise such as walking.Among the stroke risk population,the majority are extroverted(28.6%),neutral(28.6%),and irritable(36.2%).More than a quarter of patients have personality traits such as excessive commitment(20.2%),pursuit of perfection(24.9%),strong sense of time urgency(25.4%),strong execution ability,and sense of responsibility(27.7%).2.The overall age of medium to high-risk patients is older,and there is a statistically significant difference in age between the two groups(P<0.01).The number of patients in the two groups was significantly different in diabetes,hyperlipidemia,coronary heart disease and arrhythmia(P<0.05).The comparison of the total number of basic diseases between the two groups showed that the medium high risk group was greater than the low risk group,and the difference was statistically significant(P<0.01).In terms of blood pressure control,50.0%of patients in the high-risk group did not achieve blood pressure control standards,while 41.6%of patients in the low-risk group did not achieve blood pressure standards.Both groups did not attach enough importance to blood pressure.In terms of blood sugar control,64 patients in the middle and high risk group had diabetes,of which 43(67.2%)had poor blood sugar control,14 patients in the low risk group had diabetes,of which 6(42.9%)had poor blood sugar control,and the blood sugar control of the middle and high risk patients was poor.In terms of blood lipid control,there are 156 patients with hyperlipidemia,accounting for 63.7%.Excluding 44 patients with unknown blood lipid control status,among the remaining 112 patients,40(58.0%)in the medium high risk group have poor blood lipid control,while 21(48.8%)in the low risk group have poor blood lipid control.The proportion of poor blood lipid control in medium high risk patients is higher than that in the low risk group.There was no statistical difference between the two groups in the control of hypertension,diabetes and hyperlipidemia(P>0.05).In the comparison of smoking,alcohol,and dietary habits between the two groups of patients,42 patients in the medium to high-risk group had a history of smoking,accounting for 35.0%of the total number,while the lower risk group had a higher proportion of 20%,with a statistically significant difference(P<0.01).In the comparison of exercise habits between the two groups of patients,73.2%of the patients in the medium to high-risk group have exercise habits,and 98.8%of the population with exercise habits have a frequency of exercise more than 3 times per week.However,92.7%of patients have low exercise intensity and mainly take walks;66.7%of low-risk patients have exercise habits,with 90.7%of patients exercising more than 3 times a week,25.9%exercising at medium to high intensity,and the high-risk group exercising at high intensity.The difference in exercise intensity and frequency between the two groups was statistically significant(P<0.01).In the comparison between the two groups of stress,the medium to high-risk group had more work and emotional stress.The difference was statistically significant(P<0.01).3.In the analysis of blood routine indicators,the red blood cell count and hemoglobin content of the middle and high-risk group were lower than those of the low-risk group,and the Mean corpuscular volume was higher than that of the low-risk group,with a statistically significant difference(P<0.05).In the biochemical index analysis,the glucose,Lactate dehydrogenase and Glycated hemoglobin of the patients in the high-risk group were higher than those in the low-risk group,and the albumin,white ball ratio and alanine aminotransferase of the patients in the high-risk group were lower than those in the low-risk group,with a statistically significant difference(P<0.05).In the analysis of blood coagulation indicators,there was a difference in fibrinogen degradation products between the two groups,with the medium to high-risk group being higher than the low risk group,and the difference was statistically significant(P<0.05).4.In terms of traditional Chinese medicine symptoms,patients in the medium to high risk group have more traditional Chinese medicine discomfort symptoms.There are 22 differences between the two groups,all of which are more frequent in the medium to high risk group than in the low risk group,including restlessness,dizziness,tinnitus,deafness,blurred vision,dry and astringent eyes,swollen and painful eyeballs,black eyes and sockets,purple and dark lips,dry and bitter mouth,tasteless mouth,sticky phlegm,palpitations,chest tightness and chest pain,acid reflux,dry and constipation,frequent nocturia Neck stiffness,heavy limbs,sore waist and knees,numbness in hands and feet,and night sweating showed statistically significant differences(P<0.05).In terms of tongue appearance,there were differences in the dark,thin,greasy,white,and yellow tongues between the two groups,with more moderate to high-risk groups than low-risk groups,and the difference was statistically significant(P<0.05).In terms of pulse condition,there are differences in pulse sinking,smoothness,and stringency,with more moderate to high-risk groups than low-risk groups,and the difference is statistically significant(P<0.05).5.Use factor analysis and cluster analysis to summarize the traditional Chinese medicine characteristics of patients in the high-risk and low-risk groups.Based on the analysis of symptoms and tongue pulse frequency of patients in the high-risk group,a total of 11 common factors for symptoms and tongue pulse characteristics of the high-risk group were obtained through dimensionality reduction,including kidney deficiency,heart qi,qi deficiency,phlegm fire,kidney deficiency,wind fire,wind fire,spleen deficiency,liver depression,blood stasis,and fire heat.Cluster analysis was conducted on the 11 common factors mentioned above,and the clustering syndrome types were liver yang hyperactivity,heart and kidney deficiency,qi deficiency and blood stasis,and wind fire disturbance,mainly manifested as fire,deficiency,and blood stasis.After factor and cluster analysis on the low-risk group,the syndrome types were kidney essence deficiency and deficiency fire inflammation;Chest Yang deficiency,phlegm and blood stasis blocking collaterals;Deficiency of both heart and spleen;Insufficient renal essence;Mainly manifested as deficiency and stasis.Compared to the low-risk group,the medium to high-risk group has a more obvious fire phenomenon.6.In terms of vascular elasticity,compared with the low-risk group,patients in the medium to high-risk group have thicker right medial thickness and maximum medial thickness,while those in the left DC,CC α、β、PWV,LPs,P(T1),right side α、β、PWV,LPs,and P(T1)were higher in the low-risk group.The left CC,right DC,and CC of the high-risk group were smaller than those of the low-risk group,and the difference was statistically significant(P<0.05).Compared with the non fire group,the left side of the fire group patients α、β、PWV,right α、β、The PWV was greater than that of the non fire group,and the left CC and right DC were smaller than that of the non fire group,with statistically significant differences(P<0.05).Conclusions:1.Most people at risk of stroke are overweight and have unhealthy lifestyle habits such as smoking,eating fatty and flavorful foods,eating a salty diet,and having low exercise intensity.The personality traits are obvious,such as impatience,irritability,excessive responsibility,pursuit of perfection,strong sense of time urgency,strong execution ability,and strong sense of responsibility.People with higher levels of risk have poorer living habits,greater stress,more underlying diseases,and poor control.2.Compared with the low-risk group of stroke,the medium to high-risk group has poorer carotid artery elasticity,thicker inner and middle membranes,and more symptoms of traditional Chinese medicine discomfort.In terms of syndrome elements,the "fire" syndrome is more prominent.The prominent "fire" syndrome in stroke risk population may be related to poorer carotid artery elasticity. |
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