| Purpose: Clinical data of Gouty Arthritis(GA)combined with arteriosclerosis(AS)are collected,and statistical software is used to analyze the distribution characteristics of TCM syndromes and their correlation with general conditions,clinical manifestations,and laboratory indexes,and relieve headaches and objective indexes of GA-AS clinical syndrome differentiation.To provide theoretical basis for clinical treatment based on syndrome differentiation.Material and method:Patient information was collected by retrospective analysis,and a patient information database was established.After processing the collected information of inpatients,the information was input into the created Excel questionnaire,and the basic information,syndrome differentiation and syndrome characteristics of patients were recorded in detail.IBM SPSS Statistics 26.0 statistical software was used for processing,counting data were represented by frequency and frequency,and normality test was carried out for counting data,and chi-square test or correction chi-square test was used.The measurement data mean representation by plus or minus standard deviation.If it was consistent with the normal distribution using the t-test or variance test,if the information doesn’t fit the normal distribution use nonparametric tests.If the test result is p<0.05 representation the difference was statistically significant.Results:1.Syndrome type distributionThis study participants included cases 158 cases.GA in patients with TCM syndrome type distribution is as follows.Syndromes of dampness-heat accumulated in 84 cases,combined with AS33 cases(39.3%).There were 46 cases of dampness-heat obstruction combined with blood stasis,35 cases(76.1%)combined with AS1.Phlegm-stasis obstruction syndrome in 14 cases,9 cases(64.3%)were complicated with AS1.There were 7 cases with spleen deficiency and dampness syndrome,5 cases with AS1.4%;There were 4 cases with stasis heat blocking syndrome,2 cases with AS2(50.0%);Cold-damp obstruction syndrome was found in 3 cases,2 cases(66.7%)were complicated with AS.All syndromic types of GA patients were combined with AS comparative result are statistically significant differences.2.General Situation:(1)This study consists of 147 cases of male,female in 11 cases,the ratio between the men and women was 13.36:1.The comparison between the two groups have no statistical difference.6 kinds of syndrome types were compared:The gender distribution was in each syndrome type have no statistical difference(P>0.05).(2)The age of onset was greater in the GA-AS group than in the GA-NAS group,the comparison between the two groups is statistically different.6 kinds of syndrome types were compared:In the syndrome of dampness-heat obstruction with blood stasis,the syndrome of dampness-heat accumulation,the syndrome of phlegm-stasis obstruction and the syndrome of spleen deficiency and dampness-depression,The age of onset was greater in the GA-AS group than in the GA-NAS group,this was a statistical difference(P<0.05).In other types of securities,all the others were not statistically different(P > 0.05).(3)The duration of disease was longer in the GA-AS group than in the GA-NAS group,the results of comparison between the two groups were statistically different(P<0.05).6 kinds of syndrome types were compared:In every syndrome type comparison of the duration of illness all were not statistically significant(P > 0.05).3.Clinical manifestations:(1)The incidence of joint swelling of GA-AS was higher than that of GA-NAS,with statistical difference(P < 0.05).In the syndrome of dampness-heat accumulation,the incidence of joint swelling in GA-AS group was higher than that in GA-NAS group,the results were statistically different(P < 0.05).In other types of securities,all the others were not statistically different(P > 0.05).(2)The incidence of joint tenderness in the GA-AS group was compared with the GA-NAS group was no statistical difference(P > 0.05).6 kinds of syndrome types were compared:In every syndrome type comparison of the duration of illness all were not statistically significant(P > 0.05).(3)The incidence of gouty in GA-AS group was higher than that in GA-NAS group,the results of comparison between the two groups were statistically different(P<0.05).4.Laboratory indicators:(1)The blood uric acid level in GA-AS group was significantly higher than that in GA-NAS group,with statistically significant difference(P < 0.01).The blood uric acid level of GA-AS was higher than that of GA-NAS in the syndrome of dampness-heat bi and blood stasis,with statistical difference(P < 0.05),in other types of securities,all the others were not statistically different(P > 0.05).(2)There was no significant difference in the sedimentation rate of joint red blood cells between GA-AS group and GA-NAS group(P > 0.05).No statistically significant difference in erythrocyte sedimentation rate between the 6 types of evidence(P > 0.05).(3)The result of C-reactive protein level comparison between the GA-AS group and the GA-NAS group were not statistically different(P > 0.05).6 kinds of syndrome types were compared:In every syndrome type comparison of the duration of illness all were not statistically significant(P > 0.05).(4)The incidence of dyslipidemia in GA-AS group was significantly higher than that in GA-NAS group,with statistically significant difference(P < 0.01).6 kinds of syndrome types were compared:In the syndrome of dampness-heat obstruction with blood stasis,the syndrome of dampness-heat accumulation,the syndrome of phlegm-stasis obstruction and the syndrome of spleen deficiency and dampness-depression,the incidence of dyslipidemia in GA-AS group was higher than that in GA-NAS group,with statistical difference(P < 0.05),in other types of securities,all the others were not statistically different(P > 0.05).(5)The incidence of hyperglycemia of GA-AS was significantly higher than that of GA-NAS(P < 0.05).6 kinds of syndrome types were compared:In every syndrome type the comparative result between the incidence of diabetes were not statistically different(P > 0.05).(6)The incidence of hypertension of GA-AS was significantly higher than that of GA-NAS(P< 0.05).6 kinds of syndrome types were compared:In the syndrome of dampness-heat accumulation,phlegm-stasis obstruction and spleen deficiency and dampness,the hypertension rate in GA-AS group was higher than that in GA-NAS group(P < 0.05).In other syndrome type the comparative result between the Incidence of hypertension were not statistically different(P > 0.05).Conclusion:1.Three types of syndrome combined with AS are more common in three types of moist heat and paralysis,blood stasis,sputum and stasis and spleen deficiency and dampness;2.GA the older the age of onset and the longer the disease,the more likely to have AS;3.GA patients with joint swelling and tophi are more likely to have AS;4.GA patients with higher SUA levels are more likely to have AS;5.GA patients with dyslipidemia,diabetes,and hypertension are more likely to have AS. |
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