| Objective: By investigating the general situation,bone mineral density,TCM constitution,and TCM syndrome types of patients with depression,this study aims to explore the internal relationship between the TCM constitution,TCM syndrome type distribution,and related factors of patients with depression,understand the relationship between depression and osteoporosis,and explore the relationship between these influencing factors and depression combined with osteoporosis,with a view to preventing bone loss in patients with depression,To provide reference for the care and prevention of bone loss in patients with depression.Methods: A questionnaire survey was conducted among patients with depression who met the criteria for inclusion in the study at Hunan Brain Hospital(Hunan Second People’s Hospital)from January 1,2022 to December 31,2022.After obtaining the consent of the patients,the "Chinese Medicine Physical Fitness Survey Scale","Depression Dialectical Scale",and bone mineral density were measured.The general situation of patients with depression,the distribution of Chinese medicine physical fitness,the discussion of TCM syndrome types,and their related factors were analyzed,The survey data were collated in EXCEL and statistically analyzed using SPSS24.0 data software.Results: A total of 221 questionnaires were sent out in this survey and 209 were recovered.However,due to the patient’s own reasons,the study cannot be continued,and 200 questionnaires were ultimately valid.1.The average age is 46 ± 12.85 years old.There are 78 patients with osteoporosis(39.00%),42 patients with low bone mass(21.00%),and 80 patients with normal bone mass(40.00%);The incidence rate of osteoporosis in depressed people is higher than that in normal people,and the incidence rate of osteoporosis in depressed patients over 49 years old is 71.56%.2.The shortest course of disease is 1 year,and the longest course of disease is 10 years,with an average course of 2.87 ± 1.88 years.Among them,48.50% of the patients had a course of disease of more than 3 years.With the extension of the course,the incidence rate of osteoporosis increased to 61.85%.3.The gender composition ratio is 0.25:1,with 41 males and 159 females(79 of whom are menopausal).There are 14 men with osteoporosis and 64 women with osteoporosis(including 60 menopausal women).The bone loss in postmenopausal women with depression is severe,and the prevalence of osteoporosis is 76.92%.4.The frequency of occurrence of the nine types of constitution from high to low is as follows:Qi deficiency in 56 cases(28.00%),Qi stagnation in 52 cases(26.00%),Yang deficiency in30 cases(15.00%),Yin deficiency in 24 cases(12.00%),phlegm dampness in 18 cases(9.00%),calmness in 16 cases(8.00%),damp heat in 2 cases(1.00%),blood stasis in 1 case(0.50%),and intrinsic quality in 1 case(0.50%).Most of them are biased,with qi deficiency,qi depression,yang deficiency,and yin deficiency being the predisposing factors for depression.5.In patients with depression and osteoporosis,the frequency of 9 types of constitution from high to low is as follows: Qi stagnation in 23 cases(29.48%),Qi deficiency in 20 cases(25.64%),Yang deficiency in 13 cases(16.66%),Yin deficiency in 10 cases(12.82%),Peace in 6 cases(7.69%),Phlegm dampness in 5 cases(6.41%),and Damp heat in 1 case(1.28%).Most of them are biased,with Qi stagnation,Qi deficiency,Yang deficiency,and Yin deficiency being the predisposing factors for depression and osteoporosis.There is no blood stasis and intrinsic quality.6.The distribution of TCM syndrome types from high to low is as follows: liver qi stagnation syndrome in 83 cases(41.50%),heart and spleen deficiency syndrome in 74 cases(37.00%),heart and kidney yin deficiency syndrome in 19 cases(9.50%),heart and gallbladder qi deficiency syndrome in 13 cases(6.50%),and phlegm heat disturbance syndrome in 11 cases(5.50%).7.In patients with depression and osteoporosis,the distribution of TCM syndrome types from high to low is as follows: 36 cases(46.15%)of liver qi stagnation syndrome,25 cases(32.05%)of heart and spleen deficiency syndrome,6 cases(7.69%)of heart and gallbladder qi deficiency syndrome,6 cases(7.69%)of phlegm heat disturbance syndrome,and 5 cases(6.41%)of heart and kidney yin deficiency syndrome.8.Comparison of TCM constitution and syndrome types of patients with depression:(1)The frequency distribution of TCM syndrome types in patients with depression due to deficiency of qi: deficiency of both the heart and spleen(69.64%),stagnation of liver qi(21.42%),deficiency of heart and gallbladder qi(7.14%),deficiency of heart and kidney yin(1.78%),without phlegm heat disturbing the mind;(2)The frequency distribution of TCM syndrome types in patients with depression due to qi stagnation: stagnation of liver qi(75.00%),deficiency of both heart and spleen(19.23%),deficiency of heart and kidney yin(3.84%),phlegm heat disturbing the mind(1.92%),and no deficiency of heart,gallbladder,and qi;(3)The frequency distribution of TCM syndrome types in patients with depression due to yang deficiency: stagnation of liver qi(56.66%),deficiency of both heart and spleen(26.66%),deficiency of heart and gall qi(13.33%),deficiency of heart and kidney yin(3.33%),without phlegm heat disturbing the mind;(4)The frequency distribution of TCM syndrome types in patients with depression due to yin deficiency: heart and kidney yin deficiency syndrome(45.83%),liver qi stagnation syndrome(25.00%),heart and spleen deficiency syndrome(20.83%),phlegm heat disturbing spirit syndrome(8.33%),without heart and gallbladder qi deficiency syndrome;(5)The frequency distribution of TCM syndrome types in patients with depression due to phlegm dampness: heart and spleen deficiency syndrome(38.88%),phlegm heat disturbance syndrome(33.33%),liver qi stagnation syndrome(16.66%),heart and gallbladder qi deficiency syndrome(11.11%),without heart and kidney yin deficiency syndrome;(6)The frequency distribution of TCM syndrome types in patients with mild depression:stagnation of liver qi(31.25%),deficiency of both heart and spleen(31.25%),deficiency of heart and kidney yin(18.75%),and deficiency of heart and gallbladder qi(18.75%),without phlegm heat disturbing the mind syndrome;(7)The frequency distribution of TCM syndrome types in patients with damp-heat depression:only phlegm heat disturbing the mind syndrome,and none of the others;(8)The frequency distribution of TCM syndrome types in patients with blood stasis induced depression: only liver qi stagnation syndrome,none of the others;(9)Frequency distribution of TCM syndrome types in patients with idiopathic depression: only the syndrome of heart and kidney yin deficiency,and none of the others.9.Comparison of TCM constitution and syndrome types in patients with depression and osteoporosis:(1)The frequency distribution of TCM syndrome types in patients with qi stagnation and qualitative integration disease: stagnation of liver and qi(69.56%),deficiency of both heart and spleen(26.08%),phlegm and heat disturbing the mind(4.34%),without heart and kidney yin deficiency,and heart and gallbladder qi deficiency;(2)The frequency distribution of TCM syndrome types in patients with Qi Deficiency and Qualitative Syndromes: Heart and spleen deficiency syndrome(60.00%),liver qi stagnation syndrome(30.00%),heart and gall qi deficiency syndrome(10.00%),absence of phlegm and heat disturbing the mind syndrome,heart and kidney yin deficiency syndrome;(3)The frequency distribution of TCM syndrome types in patients with yang deficiency and qualitative integration disease: stagnation of liver qi(76.92%),deficiency of both heart and spleen(7.69%),deficiency of heart and gallbladder qi(7.69%),deficiency of heart and kidney yin(7.69%),without phlegm heat disturbing the mind;(4)The frequency distribution of TCM syndrome types in patients with depression due to yin deficiency: heart and kidney yin deficiency syndrome(40.00%),heart and spleen deficiency syndrome(30.00%),phlegm heat disturbance syndrome(20.00%),liver qi stagnation syndrome(10.00%),without heart and gallbladder qi deficiency syndrome;(5)The frequency distribution of TCM syndrome types in patients with depression due to phlegm dampness: syndrome of phlegm heat disturbing the mind(40.00%),syndrome of deficiency of both heart and spleen(20.00%),syndrome of stagnation of liver qi(20.00%),syndrome of deficiency of heart and gallbladder qi(20.00%),without syndrome of deficiency of heart and kidney yin;(6)The frequency distribution of TCM syndrome types in patients with Pinghe Qualitative Syndrome: stagnation of liver qi(33.33%),deficiency of both heart and spleen(33.33%),and deficiency of heart and gallbladder qi(33.33%),without phlegm heat disturbing the mind syndrome,and deficiency of heart and kidney yin syndrome;(7)The frequency distribution of TCM syndrome types in patients with damp-heat depression:only phlegm heat disturbing the mind syndrome,and none of the others;(8)There is temporarily no blood stasis and intrinsic quality in patients with depression and osteoporosis.10.Bone mass loss in patients with depression is closely related to age,gender,menopause status,and duration of disease in female patients(P<0.05)11.Although there is no statistically significant difference in the distribution of syndrome types and course of disease in patients with depression,it can reflect a related trend,with liver qi stagnation syndrome and heart and spleen deficiency syndrome as the main syndromes;The physique and course of disease of patients with depression and osteoporosis can also reflect related trends,with qi stagnation and qi deficiency being the main factors.Conclusion:1.The prevalence of osteoporosis in patients with depression is 39.00%,with a particularly significant prevalence rate of 71.56% among those over 49 years old.2.A biased constitution is more likely to suffer from depression,mainly characterized by qi stagnation and qi deficiency.3.The most common TCM syndromes for depression patients are liver qi stagnation syndrome and heart spleen deficiency syndrome.4.Although there is no significant difference in the course of depression in statistics,it can reflect relevant trends,with liver qi stagnation syndrome and heart spleen deficiency syndrome as the main symptoms;The physical constitution and disease course of patients with depression combined with osteoporosis can also reflect related trends,mainly characterized by qi stagnation and qi deficiency.5.The bone loss of patients with depression is closely related to age,gender,and course of disease. |
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