Analysis Of Professor Lv Guanhua's Clinical Experience In Diagnosis And Treatment Of Chronic Atrophic Gastritis Based On The TCM Inheritance Auxiliary Platfor

Objective:Through arranging the outpatient medical records of chronic atrophic gastritis patients treated by Professor Lu Guanhua,and using the auxiliary platform for inheritance of traditional Chinese medicine(V3.0)software to conduct statistical analysis of data,the medication rules and clinical experience of Professor Lu in the treatment of this disease were summarized,in order to provide new ideas for the treatment of this disease by traditional Chinese medicine.Methods:Patients with chronic atrophic gastritis who visited the outpatient department of Professor Lu Guanhua in the Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2021 to January 2023 were collected.The case information that met the criteria was entered into the Excel table according to the inclusive criteria,checked and uploaded to the TCM inheritance auxiliary platform system.Through the analysis of frequency results,correlation results and clustering results,the prescription medication rules and clinical experience of the tutor in the treatment of chronic atrophic gastritis were summarized.Results:1.General data: Among 154 patients with chronic atrophic gastritis,87 are women(56.49%)and 67 are men(43.51%).The prevalence rate of women is higher than that of men.Most of the patients were aged 50–69 years old,and the elderly were the majority.The five most frequent clinical symptoms of patients from high to low were: epigastric fullness,epigastric pain,belching,heartburn,and poor sleep.The tongue texture was mainly composed of pale red tongue and red tongue,with thin yellow coating and white and greasy coating.The pulse manifestation was mainly composed of wiry and thready pulse and wiry pulse.According to the statistics of TCM syndrome factors,among 154 prescriptions,seven pathogenic factors were involved,with qi deficiency and qi stagnation accounting for the most,and four pathogenic factors,namely,stomach,spleen,liver and kidney.2.Prescription analysis: The top three statistics of "four qi" of Chinese medicine were: 1071 times for warm drugs,716 times for cold drugs and 455 times for neutral drugs;According to the statistics of "five flavors" of Chinese medicine,the most frequently-used ones were pungent(36.23%)and bitter(33.32%).The number of Chinese medicine meridian tropism was up to 1468 times in the spleen meridian,followed by 1228 times in the lung meridian,and 1097 times in the stomach meridian.According to the statistical results of the efficacy of Chinese medicinals,the top three most frequently-used ones were Buxu(525),Liqi(446)and Qingre(264).The results of drug frequency statistics showed that a total of 125 Chinese medicinals were used,and the top ten in terms of frequency from high to low were: Radix Glycyrrhizae Preparata,Pericarpium Citri Reticulatae,Radix Aucklandiae,Rhizoma Pinelliae,Cortex Magnoliae Officinalis,Fructus Hordei Germinatus preparata,Radix Codonopsis,Radix Bupleuri,Poria,and Caulis Perillae.When the number of support degrees was set to 75 and the confidence level was set to 0.99,13 drug combinations,17 drug association rules and a mentor’s core drug combination for treating chronic atrophic gastritis could be obtained under the "Association Rule Analysis" module: Pericarpium Citri Reticulatae,Rhizoma Pinelliae,Radix Aucklandiae,Radix Glycyrrhizae Preparata,Radix Codonopsis,Cortex Magnolia Officinalis,Fructus Hordei Germinatus preparata,Radix Bupleuri,and Poria.Six core drug combinations were extracted using prescription clustering analysis.3.Professor Lu Guanhua’s clinical experience in the treatment of chronic atrophic gastritis: the combination of disease and syndrome,mutual reference between Chinese and Western medicine;Prescription corresponds to syndrome and focuses on constitution.Invigorating spleen qi and tonifying deficiency;Dredging liver qi to express emotions;Attack and supplement with medication can regulate both cold and heat.Conclusions: Professor LV Guanhua is good at dynamic and three-dimensional syndrome differentiation of chronic atrophic gastritis using the concept of "six-dimensional syndrome differentiation".He advocates the prescription-syndrome correspondence and the combination of disease and syndrome in clinic.At the same time,he attaches importance to invigorating spleen and dredging liver qi.He also sends herbs to attack and supplement simultaneously with cold and warm.The clinical treatment has a significant effect and is worthy of wide promotion.