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Keyword [PROTAC]
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1. Study On The Screening Of Small Molecular Compounds Targeting To Ubiquitin-mediated Degradation Of Estrogen Receptor ? And The Evaluation Of Its Antitumor Activity
2. Design,Synthesis And Biological Evaluation Of Multi-targeting Antitumor Agents And Proteolysis Targeting Chimera
3. Design,Synthesis And Biological Activity Study Of Protein Degradation Targeted Chimera For Targeted Ubiquitin Degradation Of PLK1 And BRD4 Proteins
4. Design,Synthesis And Bioactivity Evaluation Of Flavonoid Derivatives Targeting RXR? And Nur77
5. Reverse Transcriptase Structure-based And New Strategies-inspired Discovery Of Anti-AIDS Lead Compounds
6. Design,Synthesis And Biological Activity Evaluation Of CDK9 Inhibitor And Degradation Agent
7. Screening And Structure–Activity Relationship (SAR) Study Of The Protac-Based Degraders For Target Therapy In Cancers
8. Study On The Structure-activity Relationships Of MI-2 Analogues As MALT1 Inhibitors
9. Discovery And Ootimizion Of Novel Diary Pyridine/furan Ketones As Metastasis Inhibitors And PROTAC-Akt Molecules For Akt Degradation
10. Design,Synthesis And Bioactivity Evaluation Of Small Molecule PROTACs Targeting AR
11. Study On The Continuous Synthesis Method Of PROTAC Molecular Library Targeting The Degradation Of Src Homologous 2 Domain Protein Tyrosine Phosphatase(SHP2)
12. Design,synthesis And Biological Evaluation Of Small-molecule Proteolysis Targeting Chimera(PROTAC)Degrader Of Estrogen Related Receptor
13. Design,Synthesis And Biological Evaluation Of Small Molecule Degradation Agent Targeting Bcr-AblT315I Based On PROTAC Principle
14. Structural Modifications And Anti-tumor Activity Of Carthamine
15. A Novel Small-Molecule Protac Selectively Promotes Tau Clearance To Improve Cognitive Functions In Alzheimer-Like Models
16. The Role And Mechanism Of A Novel BRD4 Degradation Agent ARV-825 On Cholangiocarcinoma
17. A Stapled PROTAC Peptide Achieves Durable ?-catenin Degradation And Suppression Of Colorectal Cancer
18. Experimental Study Of Peptide Drug Development Based On Intracellular Targeted Degradation Of Keap1 To Promote Antioxidant,Anti-inflammatory,and Inhibit Hepatic Stellate Cell Activation
19. Study On The Pharmacodynamics And Mechanism Of A Novel Highly Selective BRD4 Protein Degradation Molecule In AR-positive Castrationresistant Prostate Cancer
20. Activity Evaluation And Mechanism Of Small PROTAC Molecules Targeting BCR-ABL
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