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Keyword [PROTACs]
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1. Study On The Synthesis And Biological Activity Of Chimeras Targeting To Degrade PLK1/BRD4 Proteins
2. Design,Synthesis And Biological Evaluation Of PROTACs For Degradation Of Galectin-3
3. Design,Synthesis And Bioactivity Evaluation Of Small Molecule PROTACs Targeting AR
4. Study On The Continuous Synthesis Method Of PROTAC Molecular Library Targeting The Degradation Of Src Homologous 2 Domain Protein Tyrosine Phosphatase(SHP2)
5. Design,Synthesis And Biological Evaluation Of Small Molecule Degradation Agent Targeting Bcr-AblT315I Based On PROTAC Principle
6. Development of Ligands for the von Hippel-Lindau E3 Ligase and Their Use in PROTACs, Small Molecule Inducers of Protein Degradation
7. Design And Synthesis Of A-naphthoflavone Chimera Derivatives Able To Eliminate CYP1B1-mediated Drug Resistance Via Targeted CYP1B1 Degradation
8. Structure-activity Relationship Of 2,6-disubstituted-3h-imidazo[4,5-b]Pyridine Derivatives And The Antitumor Mechanism And Druggability Evaluation Of GG041104
9. Design,synthesis And Preliminary Biological Activity Study Of MutIDH1 Inhibitors And PROTACs
10. Design And Validation Of PROTAC Molecules For The Degradation Of Fibroblast Activated Protein(FAP)
11. Design,Synthesis,and Biological Evaluation Of Small-molecule PROTACs For α1A-Adrenergic Receptor
12. Computational Methodology Study On Protein-protein/Peptide Interactions And PROTACs
13. Discovery Of Triazolopyridazine BRD4 BD1 Selective Inhibitors And Synthesis Of Pyrrolopyridone Compounds
14. Design,Synthesis,and Biological Evaluation Of Small Molecular Inhibitors And Degraders Targeting STAT3
15. Degradation Of ATAD2 To Inhibit The Proliferation And Migration Of Hepatocellular Carcinoma Cells With PROTACs Technology
16. Synthesis And Preliminary Functional Studies Of Novel Tyrosinase Modulators
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