| In order to study the efficacy and the possibility of a recombinant replication-defective adenovirus as an engineered viral vaccine, especially as an oral virus vaccine. The biological and immune characters of the recombinant adenovirus were studied in vitro, and the immune effect of different immune administrations was compared with each other with the structural gene (vp3+vp1) of HAV as target gene and adenovirus as vector. The structural gene (vp3+vp1) from...
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