Novel Magnetic Separation Methods Based On Micro-and Nano-Particles

In all analysis fields, where the analyte concentration is, for the most part, not suitable for direct analysis of crude solution even using modern instruments, pre-concentration and separation of analyte is a very important stage in all analytical procedures. Improving and enhancing the existing separation methods, and the invention of new methods, is necessary in the areas of chemical and biochemical analysis. Nanotechnology involves applying the science of the ultra-small. It encompasses the research and application of new materials and devices with one or more critical dimensions measuring between 1.0 and approximately 100.0 nanometers. This technology makes use of both past and present knowledge for designing and producing very small and specific particles in molecular sizes. With the development of nanotechnology in the 1990s, new thoughts and opportunities have appeared regarding the pre-concentration and separation of analyte. Prepared core-shell nano- and micro- particles with different core materials possess various properties and functions. They play important roles in a wide range of bio and nanotechnologies, especially in analysis and biomedicine. Recently, magnetic separation, which uses the magnetic core-shell nano and micro particles and their magnetic susceptibility to carry out the separation, have also proved to be of great importance in analysis fields. Using this method, separation is carried out by affecting magnetically susceptible materials containing extraction abilities through a magnetic field.