Study On Catalysis Of Heteropoly Acid In Fine Organic Synthesis Under Microwave Irradiation

Microwave technique has been a novel method of organic synthesis since 1980s. Compared with the conventional heating way, the microwave technique has been proved to be more useful, for example, more average heated in reaction system, more collision factor of probability in intermolecular, shorter reaction time, higher yield. Since heteropoly acid possesses numerous merits, such as an environmental amity, and an excellent activity in low temperature, a good hot stability, a unique pseudofluid phase behavior, a multifunction catalysis for acid, oxidize, and photoelectricity heteropoly acid has extensively been attracted attention in the field of catalysis by catalytic researchers. Up to now, it has been limited to report the use of microwave technique to accelerate the heteropoly acid catalytic synthesis of fine organic chemicals. In this thesis, the use of microwave technique to accelerate the heteropoly acid catalytic synthesis of fine organic chemicals has in detail been studied as follow:1. Study of microwave irradiation promoting the heteropoly acid catalytic function for condensation reaction of carbonyl compoubds(1) Based on the microwave irradiation, mono-acetal (ketal) of pentaerythritol and diacetal (diketal) of pentaerythritol, and different kinds of diacetal (diketal) of pentaerythritol were synthesized by active carbon loading heteropoly acids. 34 kinds of such products were obtained and characterized by IR, ~1HNRM and element analysis. Among these products, such compounds were for the first time reported as two kinds of mono-acetal of pentaerythritol, five kinds of diacetal of pentaerythritol, and ten kinds of different kinds of diacetal (diketal) of pentaerythritol. The results demonstrate that the active carbon loading heteropoly acids possess good catalytic reactions, small dosage, high yield, repeated use, and incorrosive equipments in these synthetic processes. Meanwhile microwave techniques importantly have expediting reaction rates where these rates based on these microwave techniques have 30 to 600 times as many as those rates by the conventional heating ways and it is unnecessary to use solvent (if need, only a little of solvent is needed) in these catalytic reactions. So the microwave techniques are provided with potential applications in large-scale industry produces.(2) The microwave synthesis of disulfonate salt-type surfactants with a 1,3-dioxane ring and the determinations of critical micelle concentration (CMC), and hydrolyzation reactions in acidic conditions, and the promoting heteropoly acid catalytic syntheses of acetoacetic ester ketal by microwave techniques were researched. During the microwave techniques, based on these...