Studies On Synthesis Heterocyclic Compound Via Electrophilic Cyclization

The thesis will to studies the synthesis of some heterocyclic compound viaelectrophilic cyclization.It mainly contists of the following four parts.Partâ… :In this part we make a summary about the history,develop,tendency of theelectrophilic cyclization reaction..Partâ…¡In this part we mainly introduce to synthesis furan derivations through electrophiliccyclization of the proparylic oxirane compound.we get to highly yields in roomtemperature and It is very friendly to environment, even we use it to synthesis somecomplex drugs and organics intermediate.Partâ…¢In this part we introduced that synthesis of polysubstituted indopyran viaelectrophilic cyclization.this reaction are occur under mild condition and gain veryhigh yields.this occurance of pyran group in both natural product and pharmaceuticalsconfer important value to this study.Partâ…£In this part we introduced the application of electrophilic cyclization in the 1,3cyclic-addition.we synthesis some poly-cyclic compounds via a new method.thismethod make the synthesis cost down quickly and friendly to the environment.