PurposeThe recovery of regional and global left ventricular function after coronary bypassgrafting (CABG) depends on the viability of ischemic myocardium in patients withprevious myocardial infarction.The purpose of this study was to assess the effects ofCABG on improvement of regional myocardial perfusion ,regional contractive functionof hibernating myocardium and improvement of LV function.Methods and Results123 patients with previous myocardial infarction , who underwent CABG operation ,were included in this study .To identify hibernating myocardium before operation,Low-dose dobutamine stress echocardiography (LDDSE ,Group I , II )was performed in 65 patients ,of those 65 patients,36 patients also underwent FDG PET (Group A),FDG PET combined with 99mTc-MIBI SPECT in 24patients(Group B),and isosorbid nitrite infuson with ISDN-99m Tc-MIBI was performed in 38 patients(Group ISDN). · The changes of regional wall motion and global function after CABG65patients were studied with LDDSE, LV wall motion was analyzed semiquantitatively by dividing the LV into 16 segments. Contractile reserved during LDDSE was defined as a decrease of one or more grades in asynergicsegments, postoperative improvement defined as a decrease of one or more grades compared with the corresponding preoperative resting image. Out of total 1040 segments, 104 were classified as hypokinetic, 173 as akinetic, 19 as dyskinetic and 28 as aneurysmal. During LDDSE, 82 hypokinetic, 51 akinetic, segments were contractile resered .Of those, 73 hypokinetic and 39 akinetic improved after CABG.In 191 segments of non contractile... |