Clinical Applications Of PET Brain Imaging In The Diagnosis Of Cerebral Infarction And Brain Tumors

[Objective] 1.To study the relationship between changes shown in ¹³NH₃ and¹⁸FDG PET at different stages of patients with cerebral infarction, between regional cerebral reperfusion in the subacute stage and tissue necrosis, between clinical diagnosis and prognosis, and among tissue perfusion, metabolism and viability. 2. To compare the accurracy of ¹⁸FDG and ¹⁸FET images in the diagnosis of pituitary adenomas and gliomas, and to help the physician select brain tracers based on the above results.[Method] 1. ¹⁸FDG and ¹³NH₃ PET brain imagings were performed in 8 normal controls(3M,5F,av.39.7 ± 11.8y).2. 20 stroke patients (15M,5F, av. 51.8 + 15.2y)underwent PET study ¹⁸FDG (total 35 scans), among whom 9 also with ¹³NH₃ concurrently (total 22 scans). Serial studies were performed in 4 patients on 0-2 days, 3days-l week, 2 weeks, 3 weeks, 1 month, 2 months, 3 months and 12 months after the onset of stroke.3. 30 pituitary adenoma patients (8M, 22F, av. 36.4+12.5y) were studied with ¹⁸FDG brain imaging (6 Cushing syndrome patients also including chest imaging), among whom 11 also with ¹⁸FET imaging concurrently. MRI was performed 40days within the date of PET studies in all patients. All cases were operated by transsphenoidal adenomectomy within 13 days after the PET study, and proved with pathology and immunohistochemistry.4. 7glioma patients (5M, 2F, av. 46.67 +15.78y)underwent ¹⁸FDG (total 9 scans) and ¹⁸FET imagings (total 8 scans). Visual and semiquantitative analyses were used to analyze the images.[Results](一) Cerebral infarction group 1. In 8controls, the distributions of cerebral activity in ¹⁸FDG and ¹³NH₃ images...