Study On The Tissue Inflammation Of Craniopharyngiomas Involving The Third Ventricular Floor And Its Relationship With Postoperative Diabetes Insipidus

Background and purposes of the researchAlthough craniopharyngioma is pathologically benign tumor, its total surgical removal bears high risk to the patients due to the involvement of its adjacent nerve structures, while its partial removal often results in postoperative recurrence. Some researchers considered that craniopharyngioma had tendency of invasion .In recent years, the increasing number of researchers have found that craniopharyngioma has no tendency of invasion, and they also found that the inflammatory reaction of craniopharyngioma tissue occurs, which brings about the inflammatory adhesion with its adjacent nerve structures, especially the third ventricular floor, and thus renders the surgical removal difficult. The inflammatory adhesion of the tumor tissue with its adjacent structures constitutes the major difficulty of its total surgical removal because the extensive separation of the inflammatory adhesion may damage such important nerve structures as hypothalamus and thus cause severe postoperative...