| Background and aimsMutiple organ dysfuncting syndrome (MODS)is one of the most sevious complications of trauma and severe infection . The knowledge of physiology and pathophysiology unde(?) MODS increased greatly in recent 30 years. To date, 'gut derived' hypothesis and imbalanced inflammatory response hypothesis were the main machenisms in the process of MODS. Intestinal bacteria translocation after intestinal-ischemia injury played an important role. Much attention have placed on the damage in the intestinal mucosa and consequences of bacterial translocation .However , the alteration of the intestinal microflora and does the bacterial translocation originate from large or small intestine are unclear. Gut mucosal immune abnormity in the mucosal immune system. However, most of data were from adult animals. The transformative patterns of structures and function of gut associated lymphocytic tissue during development have not yet been invested. Intestinal tract, which produces more than fifty kinds of gut peptides, is regarded as the largest... |