| Trauma induced osteonecrosis of femoral head (TONHT) typically happens to the patients who previously suffers from femoral neck fracture, dislocation of hip joint or femoral intertrochanteric fracture etc. There are a few cases that orgininated from hip joint trauma but the pathology has not been fully understood.In recent years, some new characteristics have been found of ONFH induced by femoral neck fracture. Firstly, as the number of the aged people and traffic accidents, violence increases, more patients have been diagnosed as TONFH that originates from increasing number of femoral neck fracture cases.Secondly, statistic data shows that with the significant improvement in operation techniques and joint materials, the cure rate of the bone fracture is improved. But with this improvement, the number of cases of TONFH has not been reduced. It is still around 10%~30% among the related cases. How to reduce the TONFH rate becomes one of the hottest fields in research. Thirdly, recent anatomy results from hip joint and deep understanding on blood circulation and blood vessel regeneration help doctors to understand more about the pathology of TONFH. Based on all those information, It is necessary to do a thorough analysis and summary. Lastly, the therapy for TONFH was mainly adapted from the treatment for non trauma ONFH. But non trauma ONFH has its very specific pathology and clinic symptoms. It has its own unique characteristics in terms of therapy and recovering. It is really necessary to develop a new set of procedures to guide the therapy and treatment for TONFH based on these characteristics.In this paper a total of 65 clinic cases were studied and analyzed based on patients' age, dislocation of the bone, treatment period, treatment method, post treatment recovering etc. That could affect the treatment of TONFH. Compelling evidence supports that TongLuo ShengGu capsule will help the recovering of TONFH patients in terms of reducing the pain in the treatment and helping recovering in walking after operation.This study combines the western and eastern methods in treating TONFH. It has been found to be able to improve the recovery rate of femoral neck fracture cases and reduce the likelihood of TONFH occurring rate as well.Early diagnosis and treatment of TONFH is very crucial. In traditional Chinese medicine practices, promoting blood circulation to remove blood stasis in the early stage and tonifying kidney to strengthen the bone afterwards are considered important to help preventing and treating of TONFH. Based on Dr. Hao Yuan's rich clinic experience, TongLuo ShengGu capsule has been developed to effectively treat TONFH. Since 1982, it has been used to successfully cure a lot of patients who suffered TONFH. A lot of clinic trails and research support the effectiveness of this medicine in TONFH treatment. This medicine is also used in successfully treating some bone fracture cases. Further research needs to be conducted to find if it can help treatments in other cases.In our experiments, a total of 65 female and 65 male New Zealand rabbits were used. They were randomly divided into 6 groups. One group that used as a reference group has 10 rabbits while all other groups have 24 rabbits each. The study model was created after the first week. The standard rabbit models of radius fracture are used to study how TongLuo ShengGu capsule assists the recovery of bone fracture.The blood analysis results show that TongLuo ShengGu capsule can effectively adjust the density of calcium, phosphor ions in the blood and help the accumulation of calcium ions and effectively improve the activeness of ALP. There is strongly related between blood micro circulation and hemorrheology. Abnormity in blood circulation and blood micro circulation are one of the main factors in affecting the recovery of bone fracture. TongLuo ShengGu capsule can help rabbits with bone fractures lower its blood viscosity, plasma viscosity, volume of packed red blood cells, improve micro circulation of rabbits with bone fractures. The bio-mechanical tests show improvement in the maximum dislocation and maximum bending force, which proves the toughness and density of bones are improved. The direct evidence from x-ray and tissue microscopy support TongLuo ShengGu capsule can help cartilage grow, bone early regenerate and bone density increase.The Guangzhou university of Chinese medicine affiliated No. 1 Hospital department of orthopaedics is the research center of Chinese medicine practice on hip disease. Since it was established more than 10 years ago, it has accumulated rich experience in treating hundreds of TONFH patients. In this paper, some treatment knowledge and practices will be summarized. |
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