A Cohort Study On The Relationship Between Nutrients Intake And The Incidence Of Hypertension And Stroke In Middle-aged Chinese

ObjectiveTo explore the relationship between nutrients intake and the incidence of hypertension and stroke in middle-aged Chinese.Methods1. A 20-year prospective study of the relationship between nutrient intake and the stroke incidence was conducted in 1038 men and women, aged 35-59 years and free of history of stroke in PRC samples from urban and rural populations in, or close to, Beijing in the north and Guangzhou in the south. The nutrient intake information was collected on three consecutive days using 24-hour recall method in the fall of 1983-1984. The stroke event occurred in this sub-sample was registered and verified by the end of 2002.2. A 10-year prospective study of the relationship between nutrient intake and the hypertension incidence was conducted in 654 men and women, aged 35-59 years and free of history of hypertension in PRC samples mentioned above. The nutrient intake information was collected on three consecutive days using 24-hour recall method in the fall of 1983-1984. The hypertension event was determined through a resurvey that conducted in the fall of 1993-1994.All nutrient intakes were energy adjusted using the residual method. The subjects were categorized into three groups according to the tritile of each nutrient intake. The relative risk of each group was calculated using COX proportional hazards model or Logistic regression model with the first group as the reference. The median intake of the nutrients in each category was used as a continuous variable to test for linear trends.