The Biomechanical Study And Clinical Observation On The Effects Of Cervical Artificial Disc Replacement On Adjacent Inferior Intervertebral Space

Cervical disc exists between interbody from C₂ to T₁,the intervertebral disc is composed of three elements:nucleus pulposus, annulus fibrosus and cartilaginous plate, and play important roles in maintaining cervical stabilization and intervertebral space height,absorbing oscillation, distributing stress evenly.Cervical disc degenerative disease are common medical conditoins treated by spine surgeons,wheras,intervertebral disc degeneration is archae-basis of pathology of Cervical disc degenerative disease. Therefore, study on morphous,biomechanics and clinical research of intervertebral disc is important.Currently, Anterior cervical discectomy with fusion is major traditional anterior managements. Cervical interbody fusion change the biomechanical environment and scarify motion and function of the segment fused,lead to the stress and range of motion(ROM) of the adjacent segement increase and acceleraton its degeneration. The cervical arthroplasty is the important technique in modern times.But can all the artificial disc fulfill the function of the disc, and the side effect on the adjacent disc,especially the inferior disc is short of systematical study on biomechanics and clinic.First of all,the homologic anatomy of cervical disc were measured ,then the sensor was used to measure the intervertebral space stress change during the biomechanical test in this study. In order to reveal the correlation between the discectomy, the intervertebral fusion and the cervical artificial disc replacement inferior adjacent intervertebral space, the change of the stress of intervertebral space between C_6/7 which applied with load of neutrality and pure moments of axial, flexion, extension, lateral bending. Then conclude the clinical effect on the adjacent inferior intervertebral space of the different disc degenerative disease treatment. Furthermore the clinical cases of the artificial disc replacement and the intervertebral fusion were followed in different time. The clinical result of the different treatment were evaluated, and the relationship of the different treatment and the inferior intervertebral space were also evaluated. Our aim was to investigate whether CADR could maintain the stress changes in the inferior adjacent segment like the intact spine and prevent the degeneration of the inferior adjacent segment in biomechanical study and...