Study And Application Of Repairing Mandibular Defect By Autogenic Morselized Bone

Preface: Located at 1/3 lower part of the face, mandible is one of the most complicated skeleton in shape, and it is the only bone which can move among all craniojaw skeleton. It participates in many important functions, such as setting up the profile of lower part of the face, taking part in chewing, biting, speaking and so on. Mandibular segmental defect or asymmetry due to congenital or acquired factors will lead to severe functional incapacitation and facial deformity. Reconstruction of madibular defect aims to repair its integrity, regain its function and rectify jaw facial deformity. As we know, there are many methods to repair mandibular defect. The main traditional method is bone transplantation which includes autogenous bone transplantation, xenoma or heterogenous bone transplantation and artificial bone substitute. Autogenous bone transplantation has positive curative effect and has been applied for a long time because it possesses many advantages, such as remaining the function of bone conduction and bone induction, containing osteoblasts, without risk of transmitting diseases, and increasing the anti-infection ability of the bone graft by vascular anastomosis or pedicle skin flap bone transplantation. But it still can't achieve ideal repair, because of lack of donator, difficulty in shape carving, and auto damage. Our research group has accumulated rich experience of operation on...