Effects Of The Orthodontic Tooth Movement On The Periodontal Tissue Remodeling And Pregnancy In The Pregnant Rats

Background and Objective: Among the adult orthodontic patients, there are a lot of young females who are at the reproductive age. In orthodontic practice, it is very usual that an orthodontist would face some female patients, who are conceiving children or want to do that during the treatment period. There also are some pregnant women who intend to seek orthodontic treatment. But what is the influence that the orthodontic treatment would exert on the human pregnancy? Is it safe to perform the orthodontic treatment during the gestational period? Could the orthodontic force impair the development of the fetus? Is it having different effects on tooth movement velocity when moving tooth at different trimesters of pregnancy? Meanwhile, during the gestational period, what are the effects of the orthodontic tooth movement on the periodontal tissue remodeling? What is the expression pattern of the bone remodeling factors in the periodontal tissue during the pregnacy? To date, there seldom exist any researches about these concerns. For the pregnant patients' sake, investigation into these questions is invaluable.The maintenance of normal pregnancy depends on the rhythmic secretion of progesterone by ovaries and placenta, which are controlled by cortex-hypothalamus-pituitary axis. Recently, it was found that progesterone receptors exist in the periodontal tissue, and the bone remodeling, the degradation...