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Study Of Liposome Of Biomimetic Mineralization In Human Hard Tissue

Posted on:2007-01-21Degree:DoctorType:Dissertation
Country:ChinaCandidate:Z H LiangFull Text:PDF
GTID:1104360185994587Subject:Oral and clinical medicine
Abstract/Summary:PDF Full Text Request
IntroductionDuring the formation of human hard tissue ,cells control the mineralization,which regulate the concentration of ions, pH value,depressor formation in mineralization. The basical function is cell is compartment ,through the compartmental control the reactant concentration, oritation, catalyzation ,balance motion. Matrix vesicles come from osteoblast, cartilage cell,odontoblast. Matrix vesicles budded from cell, then apart from cell to form self-governed organelle. Which reserved the cell film and cell liquid. The liquid contained PO4 , ALP,and so on .calcium pump in film of matrix ,calcium ion and PO4, formed Ca-lipid-PO4 copulation..calcium ion and PO4 concentrate in the matrix to form amouphorous calciumphosphorylate (ACP) and released to extrocell transform to HA..Matrix calcification completed through matrix vesicle excretion.Nature's mineralizers use small amounts of organic macromolecules as template to manipulate inorganic crystal nucleation, growth, microstructure, and consequently the properties of their mineral-based materials. These...
Keywords/Search Tags:liposome, matrix vesicles, gelatin, biomimetic mineralization
PDF Full Text Request
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