The Study Of Mimetic Oligo-peptide Of HSV Glycoprotein Screened From Phage Random Peptide Library

Herpes simplex virus(HSV), a common pathogen throughout the world, can cause a variety of clinical illnesses that damage human's health severely. So far, no safe and effective HSV vaccine has been developed yet by reason of possible existing oncogene in it's genome. Recently, progresses have been made in developing HSV subunit vaccine or genetic engineering vaccine based on the high antigenicity of HSV glycoproteins. While, vaccines made of just one kind of glycoprotein show low antigenicity and can not protect the vaccinated animals from the virus infection thoroughly. Therefore, vaccines containing several immunogens with high protective antigenicity are being developed, and are expected to induce higher and stronger specific immunity.