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The Preparation Of Gene Vaccine And Investigation Of Its Anti-tumor Activity For Bladder Cancer

Posted on:1996-03-10Degree:DoctorType:Dissertation
Country:ChinaCandidate:F S JinFull Text:PDF
GTID:1104360185996823Subject:Surgery
Abstract/Summary:PDF Full Text Request
Bladder cancer is one of the most commen tumor in urinary sgstem, and its recurrence rate is very high. So management of bladder cancer be-comesone of the difficult problems in clinic. The main causes of so high recurrence rate of bladder cancer include the immunological suppression, the growth of residul and implanted cancer cells, and the developmental multi—foci in nature. Experimental and clinical investigations have both confirmed that interlukin-2 (IL-2) and some other immune therapeutic methods have effectiveness for bladder cancer.Gene therapy is one of the most important advance in medical biological field in 90 ages. Gene vaccine and antisense technology are regarded as the most effective procedures in gene therapy for cancer. According the known implicated factors of the recurrence in bladder cancer and the char-...
Keywords/Search Tags:bladder cancer, gene therapy, interleukin-2(IL—2), gene vaccine
PDF Full Text Request
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