| The Diabetic Nephropathy(DN) is a special, serious and chronic tiny bloodvessel complication of Diabetes Mellitus(DM),and it' s one of the importantcauses of leading the chronic disease of the crocked-up function of kidney .Aswas reported, about 40％of the patients of End Stage Renal Disease(ESRD) arecaused by DN.In recent years, as the development of the standard of livingand the prolong of human' s life, the number of DN patients is obviouslyincreasing, and the incidence of DN is ascending, and it's harm to humanis rising. At present, many experts at home and abroad have paid attentionto DN. The person who suffered from DN may be dying when the state of DN isbecoming serious at the anaphase. Unfortunately, the perfect medicament ofcuring or leave something DN is not made. By reading many clinic reports aboutcuring DN, the writer found that the Chinese Medicine had been used to cureDN, and the Chinese Medicine really had a helpful effect on curing DN. In orderto establish the theoretical foundation of cure DN and draw more attentionto cure DN, the writer summarized some rules of using medicament to cure DNafter learning some effective experience from the clinic curing.Part 1 Study on the Literature ReviewObjectives and Methods: According DN, the writer summarized thepathogenesis of DN and brought forward some Rx after reviewing most of therelative literature about curing DN. The writer also wants to provide sometheoretical bases for curing DN after studying the actuality of curing DN bymodern medicine nowadays.Conclusion: In recent years, the study about Chinese Medicine curing DNhas got great achievement. The clinic research has showed that the Chinese Medicine had a better effect on curing DN, and the experiments research hadchanged into discussing the mechanism of suffering from DN from simple researchon the effect testing or comparing. The basic study is transforming into thelevel of cell molecule biology from the whole level. But there are manyshortages in the past research. The writer found that there is no. The writeralso found the effects of different Chinese Medicines have many discrepancies,and the datum for studying are short of contrast. The writer suggested thatthe unitive standard of diagnosing, evaluating the effect and therapy withsyndrome differentiation of Chinese Medicine in China should be establishedmore comparably and more reasonably.Part 2 Literature Computation Study1. Study related literatures and reportsObjective: Analyze the survey about DN-treated resent years, and summarizethe forepart, syndrome and cure in the period of clinic, in order to instructthe clinic.Method: choose the literature and report on the clinic accord with theDN-diagnosing criterion from 1995 to 2006, set up the Access database of DN,according to the order from note to database to statistic to result, usingstatistic software, process Frequency Analysis to analyze the distributingposition of syndrome and prescription and medicine(including medication, sort,and so on), process Cluster Analysis to summarize the composition of themedicine, and list the primary medicine to analyze.Results: 352 articles were noted in the research, 73 of these are about theearly period of DN, and 134 are about clinic period, and 145 are about elsemotif. In the 73 articles, 103 medicines were used, and 37 medicines were usedmore than 5 times in those, the former three position were Radix Astragaliseu Hedysari(11.04％), Radix Salviae Miltiorrhizae(8.57％), RhizomaDioscoreae (6.26％),and the primary syndrome sort were asthenic splenic qiand asthenia renal qi, asthenic splenic qi with blood stasis, as well as yinasthenia, with endopyrexia.Howerer, in the 134 articles, 159 medicines wereused, and 56 of those were used more than 5 times, the former three positionwere Radix Astragali seu Hedysari (9.07％), Radix Salviae Miltiorrhizae (7.24％),Poria (46.01％), and the primary syndrome sort were asthenic splenicqi and asthenia renal qi, asthenic splenic qi with blood stasis, as well asyin asthenia, with endopyrexiat. In the summary, we can conclude: in the 352 articles, 203 medicines were used, 76 of those were used more than 5 times, theformer three position were Radix Astragali seu Hedysari(7.79％), Radix SalviaeMittiorrhizae (7.04％),Poria(5.03％), the primary medicines used to cure wereinvigorating qi medicine, promoting blood circulation to remove blood stasismedicine and removing dampness and promoting diuresis medicine, thefrequencies of these achieved 55.96％, the primary syndrome were astheniarenal qi, blood stasis asthenic splenic qi, yin asthenia and damp heat.Conclusion: From the description of the 352 documents, it may be seen thatthe main symptoms of DN: blood stasis; asthenic splenic qi; asthenia renalqi; yin deficiency; etc.. but the blood stasis throughout, As a matter of fact,blood stasis is found in every clinical, aside, the symptoms of deficiencyboth spleen and kidney also makes a certain ratio, which ofen been found fromthe diabetics. and the others, For example, the symptoms of hypoyin,bothdamp heat and ulcer tuebid substance, usually, occurring in the process ofasthenia of both yin and yang at an advanced period of time of diabetics. Duringthe time of treating with medicine, it should be treated according to the styleof the different periods of diabetics with medicine of tonifying qi,promoting blood circulation to remove blood stasis, or medicine of removingdampness and promoting diuresis and etc. As a result, when treating at aclinical diagnosis, it should be treated according to concrete realities atdifferent ages.2. Analyzing the datum of disease caseObjective: By study the datum of DN in the Disease Case Room in GuangzhouChinese Medicine University, the writer analyzed the common instance of cliniccuring DN.Methods: By choosing the disease case according with the standard ofdiagnosing DN from the NO.1 Appertain Hospital of Guangzhou Chinese MedicineUniversity, the writer try to establish the databank of curing DN. Followingthe order of "Notes—Build bank—Statistic—Export result", the writerstatistics the medicine used kind, meridian distribution nature, calculatedthe ratio of using frequency, and concluded the common rules of using medicineto cure DN.Results: Among the 303 persons who suffered from DN, 84％have the syndromeof asthenic splenic qi and asthenia renal qi, blood stasis, internal stagnationof phlegm and yin asthenia. The former three frequency of using medicine are: Poria (12.34%), Radix Astragali seu Hedysari (8.41%), Radix SalviaeMiltiorrhizae (8.04%). The common Chinese Medicine are these which have thefunction of removing dampness and promoting diuresis, tonifyingqi, invigorating qi, and promoting blood circulation to remove bloodstasis, activating blood flow and removing blood stasis.Conclusion: These DN patients chosen in this research are all in PeriodV, and the function of their kidneys has damaged in some degree. The mainsyndromes are asthenic splenic qi and asthenia renal qi, and bloodstasis, phlegmatic retention, tuebid substance are the main pathology products,and the methods of curing are to strengthen the splenic qi, renal qi andremoving dampness and promoting diuresis, etc. The DN patients in differentarea showed different characters because of the special physical geographyand the clime climate, the methods of using medicine should adjust to localconditions and different personalities.
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