| Objectives: the main objective of this thesis is to provide a guidance for acupuncture-treating trigeminal neuralgia (TN) with proper acupuncture points by studying the therapeutic effect of the scalp acupuncture on the trigeminal neuralgia (TN) and its function mechanism through the experiment on model rats in which the effect of the head-point needling of both-side sensing part on the response, the neurotransmitter and the electrophysiological issues.Methods:1. The microinjection of penicillin G-K into arachnoid space at obex is used to get the model of the rat trigeminal neuralgia (TN).2. The number of the aching and its lasting time, and the induced reaction masculine time were recorded for the head-needling samples, the carbamazepine-samples and the model samples, respectively, after the model of the rat trigeminal neuralgia (TN) was obtained.3. The content of the blood plasma substance P (SP) and theβ-EP were measured for the head-needling samples, the carbamazepine-samples, the model samples, and the artificial operation samples, respectively, using the radiation-immunity method.4. The delitescence and the basic pain threshold of the infraorbital nerve induced masseter muscle electronic reaction were measured with the electromyography for the head-needling samples, the carbamazepine-samples, and the model samples, respectively.Results:1. In terms of the ethology issues, the head-needling obviously reduced the number of the aching and its lasting time, and the induced reaction masculine time (P<0.01), as compared with model samples; however, the head-needling showed no obvious difference from the carbamazepine-samples (P>0.05)2. The head-needling obviously reduced the content of SP (P<0.01), as compared with model samples; however, the head-needling showed no obvious difference from the carbamazepine-samples (P>0.05) .3. The head-needling obviously increased the content ofβ-EP (P<0.01), as compared with model samples and artificial operation samples; however, the head-needling showed no obvious difference from the carbamazepine-samples (P>0.05).4. The delitescence was obviously lengthened in the case of the head-needling, as compared with model samples, with the peak at 30-60 min; in the staring 30 min, the head-needling increased the delitescence, as compared with carbamazepine-samples; the instant delitescence was increased in the carbamazepine-samples as compared with model samples, with a lengthened delitescence in the case of 0min, 30min, 60min, 90min, 120min, and no peaks observed.5. The basic pain threshold was obviously increased in the case of the head-needling, as compared with model samples, with the peak at 30-60 min; in the staring 30 min, the head-needling increased the basic pain threshold, as compared with carbamazepine-samples; the basic pain threshold was increased in the carbamazepine-samples as compared with model samples, with a lengthened delitescence in the case of 0min, 30min, 60min, 90min, 120min, and no peaks observed.Conclusions:1. Scalp acupuncture can reduce the attack number in the model animal of TN, shorten the duration of spontaneous reaction, lighten the degree of the attack ,which provides an ethological guidance for treating the trigeminal neuralgia (TN).2. Scalp acupuncture can decrease the content of SP, and increase the content ofβ-EP, which provides a theoretical basis for treating the trigeminal neuralgia (TN) based on the neurotran-smitter.3. Scalp acpuncture can increase the delitescence and the basic pain threshold, which provides an electrophysiological theoretical basis for treating the trigeminal neuralgia (TN).
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