The Study Of CT Volume Perfusion Imaging In Solitary Pulmonary Nodules

Objective: investigate the technique and clinical value of volume perfusion imaging derived with dynamic CT in solitary pulmonary nodules (SPNs). Materials and Methods: patients with. SPNs (57maliagnant; 15 active inflammatory; 13 benign)underwent CT volume perfusion imaging , among whom the tissue samples of 35 patients with bronchogenic adenocarcinoma were available to be studied immunohistochemically in our institute. Results: statistically significant differences were found between interval scanning and successive in quantifiable parameters derived with CT volume perfusion imaging. There were statistically significant differences among three sections and among three groups nodules (maliagnant; active inflammatory; benign), in quantifiable parameters. Quantifiable parameters didn't correlated with the nodules size, while correlated positively with MVD in bronchogenic adenocarcinoma. Conclusion: Interval scanning is suggested in CT volume perfusion imaging. 2 The volume perfusion of the nodules is inhomogeneous. 3 No significant correlations were found between the quantifiable parameters derived with CT volume perfusion imaging and nodules size. 4 The CT volume perfusion imaging is helpful in differentiating solitary pulmonary nodules. 5 The quantifiable parameters of CT volume perfusion imaging reflect MVD in bronchogenic adenocarcinoma.