Effects Of Vibration Training On Exercise Performance Of Rat Skeletal Muscle And The Possible Mechanism

Objective: The present study was designed to examine the effects of different vibration trainings on the exercise capacity, and further explore the underlying mechanism of cellular and molecular biology. Methods: 42 male Sprague-Dawley rats were used to establish different vibration training models. Exercise capacity in rat skeletal muscle was evaluated, the chemical levels in muscle tissue, muscle creatine kinase (CK) and myocytes Mechano growth factor (MGF) expression levels were tested. Proliferation and protein content of satellite stimulated by vibration were detected through muscle myo-satellite cell culture experiments. Results: Compared to the control group(CC), scores of swimming and grasping power in the medium-frequency vibration prolonged group(ML) were significantly improved. In addition, the relative quality of the gastrocnemius muscle, fiber cross-sectional area, CK and MGF mRNA expression was significantly increased in ML group. Cultured quiescent satellite cells were subjected to mechanical stretch in a Flexer Cell System. In response to stretch stimulation, the multiplication ability and protein content in satellite cell were higher than those in the control group. Conclusions: Vibration training may stimulate proliferation of satellite cells and the expression of MGF mRNA, promote muscle hypertrophy and CK enzymes activity, then lead to the enhancement of exercise performance.