Lanthanide Complexes Composite Materials And The Co-asbembly Of Peptides/Lipids

Attapulgite clay, natural silicate nanorods, can form nanocomposites with extreme chemical stability and remarkable exposure durability. Combining luminescent lanthanide complexes with attapulgite to improve their stability and even luminescent properties is fascinating, promising but challenging in the lanthanide composite field. A europium complex Eu(tta)3(H2O)2(Htta=2-thenoyltrifluoroacetone) was covalently coupled on attapulgite (and MCM-41or ZSM-5for comparison) via ligand exchange reaction, generating the first example of attapulgite-based ternary europium complexes. The composites were characterized by29Si magic-angle spinning (MAS) NMR, CHN elemental analysis, inductively coupled plasma-atomic emission spectroscopy (ICP) for Eu3+contents, X-ray diffraction (XRD), and UV-vis absorption spectra. The results indicate that Eu3+complexes bond covalently to the outer surfaces of attapulgite, permeate the channels, and are stuck with the complexes bonded to the inner walls of the pores in MCM-41, or invade into the channels of ZSM-5after decomposition. These structures were further evidenced by luminescence efficiency and coordinated waters of the complexes linked to matrixes. The composites display more efficient emission, enhanced thermal stability, and improved exposure durability in comparison with the isolated complexes, due to interactions of the complexes with the matrixes. The most efficient emission of attapulgite-based complexes among the composites results from the uniformly structured ternary europium complexes. At last, we applied this kind of attapulgite-based lanthanide composites to bio-imaging, and proved that they could be used as bio-labels after appropriate medication on the surface.Drug carriers of polymer and lipid particles often struggle to meet certain clinical expectations, such as size, stability, shape, capacity, and compatibility. The co-assembly of multi-components in solutions not only provides a variety of morphologies with outstanding control, but also presents multiple signals in a three-dimensional. In order to easily tune the morphology and stability of the peptide-based self-assembly system, we here show a facile co-assembly strategy with the help of mainly hydrophobic interactions. The peptide amphiphile consists of a peptide backbone with side conjugation of PEG-2000as hydrophilic block, and two alkyl tails attached to the N-terminus of the peptide as the hydrophobic part. DMPC, which is one of the essential compounds in cell membranes, serves as a second amphiphile for the co-assembly behavior with peptide. The mixed system of DMPC/P mixtures shows that the morphologies and stability of the assembled structures can be nicely controlled by changing DMPC/P ratio and modifying preparation strategy.