Evaluation Of The Risk Of Cardiovascular Events Induced By Excessive Exercise In 40-49-years Old Adults

Purpose:In order to prevent exercise-induced cardiovascular events, we want to look for some indicators that could evaluate and predict the risk of cardiovascular events happened during exercise, improving safety during the fitness exercises in adults.Methods:A questionnaire survey was conducted among the urban non-manual workers aged 40-49 by IPAQ, without serious disease and mobility impairment. Subjects performed the graded exercise test (GXT) on a cycle ergomater of Custo-med, starting with 25 w and adding 25 w at 2 min intervals until the subject experienced any discomfort or irregularities which were referenced from general indications for stopping an exercise test in ACSM's Guidelines for Exexcise Testing and Perxcription(eighth edition)in 2009, which was include:objective indicators of abnormal ECG and BP value and subjective indicators of RPE and fatigue. According to the different terminal indicators who had experenced, the subjects has been devided into three groups. The individual who had been interrupted by the 4th or the 6th indicators but not by the 1st, the 2nd or the 3rd one entered Perceived group (P group). And if someone appearing the 1st, the 2nd or the 3rd one would enter the Cardiovascular group (C group).The performance, RPE, ECG, Bp and V02 were monitored during the test. Before GXT, index of body mass had been measured. Differential ECG (DECG) and EEG were collected by Omegawave System. Peripheral blood had been collected before and immediately after exercise respectively. The levels of serum lipid profiles and myocardial enzymes had been tested.Results:1.271 subjects (136 male and 135 female) were selected in our study. Among them 113 men and 123 women were interrupted during their GXT, The others who had none symptom would be treated as the Asymptomatic group (A group).Compared with A group, the other two groups completed lower intensity and had lower HR Reserve. Female was significant.2. Compared with A group, waist circumference, CK-MB was increased significantly in C group in men, and middle-high intensity physical activity, LDH1/LDH, SDSD, PNN50, LF/HF, HF norm were changed significantly in women in the C group.3. Compared with normal group with ST segment, waist circumference was dropped significantly in men in 2-mV depression group, and SDNN, rMSSD, TP, LF, LF/HF, HF norm decreased significantly in women in the same group.Conclusion:1. Increasing of the level of serum myocardial enzyme indicated the cardiovascular risk during exercise was elevated.2. Among male adults, when waist circumference was up to 88cm or more in men, the cardiovascular risk during exercise was elevated. Reaching more than 94cm would enlarge the risk of ST segment depression during exercsie. 3. The cardiovascular risk during exercise would be elevated when the physical activity of middle-high intensity was lower than 3800MET-min/wk in women.4. When HRV decreased, the cardiovascular risk during exercise, including ST segment depressing more than 0.2mV, would be enlarged in women.