Application Of Ultrasound To The Study Of Liver And Kidney And Cardiac Microcirculation Blood Flow Velocity And Blood Flow

Objective: To use ultrasound microbubbles for real time direct quantification of blood flow velocity in normal liver and kidney microcirculation in order to investigate the change in blood flow velocity and blood flow status of microcirculation .Methods: Blood flow velocity of normal microcirculation in liver, and kidney were determined using DFY type ultrasound imaging quantitative analyzer among 10 experimental dogs. Blood flow status was observed,. and blood flow velocity was measured.Results: The blood flow velocities in liver, and kidney were 0.82±0.17 mm/s, and 1.19±0.38 mm/s, The moving tracks of microbubbles in kidney and liver microcirculation were mainly straight lines or curves of lesser curvature. The microcirculation velocity was not steady, but maintained at a comparatively low level, with a remarkable difference from that of large vessels. The blood flow was manifestated as linear flow and line grain flow under contrast agent of high concentration, but grain flow and slow flow under contrast agent of low concentration. The microbubbles flew in all directions. The average blood flow velocity in kidney microcirculation was higher than that in liver microcirculation(P<0.05).Conclusion: A noninvasive, dynamic real time, simple, and direct method to determine microcirculation blood flow velocity in deep organs is successfully established. Objective: The study aims to investigate blood flow velocity and blood flow status of microcirculation in normal myocardium, ischemic myocardium by using ultrasound microbubbles.Methods: Blood flow velocity of normal microcirculation in myocardium was determined, using DFY-ⅡUltrasound Imaging Analysis Software among 15 experimental dogs. Dog models of myocardial ischemia with coronary stenoses of different degrees were established; blood flow status in ischemic myocardium was observed, and blood flow velocity was measured.Results: The blood flow velocities in normal myocardium was 6.25±1.27 mm/s. In dogs with 50%, 90%, and 100% myocardial ischemia , the myocardial blood flow velocities were 2.30±0.57 mm/s,0.10±0.04 mm/s, and 0.05±0.01 mm/s, respectively. Blood flow gradually slowed down as the artificial stenosis aggravated (P < 0.05). Conclusion: A noninvasive, dynamic real time, simple, and direct method to determine microcirculation blood flow velocity in deep organs is successfully established. Objective Through simple tools and the method of combining color Doppler produced different degrees of coronary stenosis.Methods The first measure and calculate the area of LAD, Corresponding to the thickness of the needle by using the tie wrap in the LAD then pull it out and produce varying degrees of coronary stenosis. Color Doppler and then verify.Results Successfully produced a coronary stenosis 50% and 90%. Verified by color Doppler produced a narrow area and color Doppler data between the two groups was no significant difference (P> 0.05).Conclusion This study is a different degree of coronary artery stenosis produced a simple, convenient, accurate, low-cost new method. Color Doppler method can be validated to ensure the accuracy of stenosis after ligation. For the various studies on myocardial ischemia provides a convenient conditions. It is particularly suitable for the study of relevant ultrasound topics.