Gukang The Effects Of Calcium And Phosphorus Metabolism In Ovariectomized Rats

Osteoporosis is a desist that formed by multiple reasons. The character of osteoporosis is low bone density and microarchetectural deterioration of hone tissue, which lead to increased fragility of hones and obviously higher percentage of fracture risk. Due to the extension of human life, the fracture lead by osteoporosis increasing and its complications threats these aged population. herefore, osteoporosis isattractinga lot of attention from all over the world. There is no such a name steoporosis?in traditional Chinese medicine, according to the major complains of patients, it may be classified in u Wei?From the pathology point of view, most of the schools believes that hormone changes, nutrient imbalance and activity levels are the key points to occur osteoporosis. Besides that the immune and inherit factors are closely related t.o osteoporosis. The declined sex gland would lead to osteoporosis was observed long time ago, but the receiver of cstrogen in osteoblast was found not long ago. People then real izod that estrogen can not only depress osteoclasia but also increase osteogensis. To evaluate the risky factor of osteoporosis, the treatments have include changing life style of patients. In the nutrition side, the host quantity For absorption of calcium and phosphorous , protein, fat, vitamin, mineral~etc. And the most important is the absorption and metabolism of calcium and phosphorous. My tutor Professor Liu Qingi set up three basic theories of osteoporosis based on his years clinic experience, they arc idney master bones?, idney and spleen are "related?and lood stasis" . Under these three basic theories, we may locate pathological position, which are idney? "spleen?and tasis" . fter locating the pathological position, according to the three Chinese medicine's point of view ?--alance, entirety, differentiate, we set up the principle of treatment for osteoporosis, which is invigorate kidney? "strengthen spleen?activate blood". From the support of all these theories we formed the formulaGu Kang. Gu Kang had built a good reputation among patients. In this experiment mainly focused on the influence of Gu Kang at the metabolism of calcium and phosphorous of castrated rats. Through some toxic elements Uk aluminum, Cd, lead, who will lead the lost of calcium and phosphorous. The result of this experiment shows that: 1. Successful molding. 2. Gu Kang can promote the content of calcium and phosphorous of gelded rats. 3. Gu Kang is adjusting the whole body to achieve the treatment goal. 4. From calcium and phosphorous?point of view, Gu Kang has the same effort as the positive contrast section. 5. In Gu Karig section, Cd is less than the positive contrast and model section.