Forefront Of Dredging Capsule For Chronic Prostatitis Mechanism Of Experimental Research

Objective: Through performing laboratory investigation, we discuss the mechanism of qianlieqingshu capsule which has the use of heat clearing and dampness elinting , activate blood circulation and remove stasis.Method: Adopting normal rat or mouse, chronic bacteria and nonbacteria prostatitis model, prostate proliferation model, and other corresponding model, and through seting up different control group, we performed laboratoty investigation to turn out weather qianlieqingshu capsule can cure chronic prostatitis, depress prostate proliferation, activate blood circulation and remove stasis, antixidant, defervesce and ease pain.Conclusion: The result of most pharmacology experiment point out qianlieqingshu capsule of high, middle and low dosage have pharmacology functions as follows: (l)It can drastically cure rat who suffered from chronic prostatitis. (1)Dastically depressed prostate weight qutiety of rat model. (2)It can dastically improve pathologic change (mesogahia's infammatory cells infiltration, infammatory cells proportion enlagement, gland and gland cavity wasting away, the numerous of gland and gland cavity decreasing, gland and gland cavity's proportion, perimeter, the biggest diameter, the least diameter, equivalent roundness daimeter, were also improved) of chronic nonbacteria prostatitis rat which is made by injecting agar. (2)Depressing prostate proliferation: Depressing prostate proliferation which is made by testosterone propionate. (3)Activating blood circulation and removing stasis: qianlieqingshu capsule of high and middle dosage can improve the abnormal index of blood examination of rats who suffered from chronic prostatitis which is bring out by cobibacillus. Comparing with model group, it can drastically improve abnormal numerical value of blood viscocity, red cells compression volume, red cells assemble index and the cotent of fibre albumen dastically depress). (4) Antiinflammation: Dastically depressing acute effusive and proliferative inflammatoty process. (1) qianlieqingshu capsule can ease auricle swelling of mouse which is made by injecting xylene.(2)Qianlieqingshu capsule of high dosage can dastically inhibit metatarophalangeal inflarnmatoryswelling of rat which is made by injecting egg white, ï¹’ianlieqingshu capsule also can depress grannuloma growth of mouse. (5) Defervescing: It can defervesce rabbit who suffer from fever which is made by injecting bacteria endotoxin. (6)Easeing pain: (1)The experiment of mouse hot board measure showed that qianlieqingshu capsule of three dosage can dastically ease pain. (3)The experiment of mouse tortion measure showed that high and low dosage qianlieqingshu capsule also can dastically ease pain.