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Clinical Evaluation Of The Different Point Of Apoplexy

Posted on:2005-11-21Degree:DoctorType:Dissertation
Country:ChinaCandidate:B MaFull Text:PDF
GTID:1114360125959454Subject:Traditional Chinese Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective To investigate on the outcome assessment indices for stroke in its different stages,while finding out relevant indices from the information provided by the four diagnosticmethods in TCM for stroke; to improve the survey form of the four diagnostic methodsin TCM for stroke, in attempt to provide a standardized information collection methodof the four diagnostic methods for stroke.Methods This research is an initial research of a program project of the Ministry of Scienceand Technology—Chinese Herbal Medicine Standardization and Related TCM ClinicalEvaluation Standards (Project number: 2001DEA2001O). This research combinesprospective follow-up study and cross-sectional survey. A modern medicine surveyscale corresponding to different stages of stroke is used, together with our user-definedfour diagnostic methods information scale for stroke on the 7th and 14th days of attackof 140 prospective cases and 28th-180th days of 102 cross-sectional cases.Results1. The degree of physical role damage is the greatest, while the degree of bodily pain is the least after a stroke attack, as seen from the survey analysis of quality of life of patients in their convalescent stage. The quality of life in the convalescent stage of the cerebral infarction group and the intractable hemorrhage group in their convalescent stage showed a significant difference. As of physical function, the quality of life of the cerebral infarction group showed to be better than the intractable hemorrhage group, while the intractable hemorrhage group showed to be better than the cerebral infarction group in emotional role.2. From the relative frequency of the information gathered through the four diagnostic methods, the Chi-square test, the factor analysis, and their correlation analysis with the symptom scale, the following can serve as outcome assessment indices of stroke: fatigue, bad breath, night sweat, slow reaction, apathy, shoulder pain, swelling of hands, finger spasm, weak limbs, staggering gait, distorsion of mouth and tongue, lalopathy, choking, and numbness of limbs.3. Hierarchical clustering analysis results suggest that the "phlegm syndrome", "heat syndrome", and "deficiency syndrome (qi deficiency and yin deficiency)" are predominant on the 7th day of the stroke arrest; the "phlegm syndrome", "heat syndrome", and "deficiency syndrome (yin deficiency)" predominant on the 14th- 4 - 中风病不同时点临床评价指标的研究 day; while the "deficiency syndrome (qi deficiency and yin deficiency) predominant on the 28th day. This paper is only an initial study of the outcome assessment indices for strokefrom different angles. The indices chosen still need further screening and evaluatingin order to be considered into the outcome assessment system of stroke.Conclusion The four diagnostic methods information scale for stroke constituted by ourresearch team can be used for the clinical information gathering of stroke. Thestandardization scheme of clinical information gathering of stroke is reliable; however,the quantification standards of some TCM symptoms of stroke need to be emended.The mode of outcome assessment of stroke can be an integration of the modernmedicine assessment scale and the TCM symptom assessment scale. Correlation analysis shows that partial outcome assessment indices of the fourdiagnostic methods in TCM for stroke can be replaced by the significantly relatedneurology scale. One-way analysis method and multivariate analysis method can unveil TCMoutcome assessment indices for stroke; however, due to its complexity, there is still aneed to integrate other data mining statistic methods.
Keywords/Search Tags:Data mining, Four diagnostic methods information, Methodology, Outcome Assessment, Stroke, TCM
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