Gossypol On The Anti-differentiation Effects And Mechanisms Of The Blood Tumor Cell Lines

Background: Hematopoietic neoplasms (HN) are a group of refractory life-threatening disorders that have a propensity to occur during adolescence. Increasing environmental pollution resulting from industrial development has been associated with increased HN morbidity rates. Traditionally, radiochemotherapy has been the choice of treatment for HN; however, it also produces serious side effects such as hemorrhage and infection. The side effects dramatically impact patients' quality of life and discourage long-term use of therapy. There is, consequently, a critical need for novel, more effective drugs with fewer side effects in HN therapy. Gossypol, a...