Skeletal Muscle Fatigue Resistance Training, Mechanical Performance And Dynamic Cardiomyoplasty Experimental Study

The purpose of this experiment was to study the trans-formation of skeletal muscle, the difference of physical characteristics between fatigue and fatigue -resistant skeletal muscle, and the effects on the heart of dynamic cardiomyoplasty.In the research of the transformation of skeletal muscle, 7 mongrel dogs were divided into 2 groups. In group one,the right latissimus dorsi. muscle was freed from the chest wall.After a 2 to 3 weeks vascular delay period,the muscle was conditioned with a 2HZ stimulation of the thoracodorsal nerve diectly for 8 weeks. In group two, the collateral blood vessels to the right latissimus dorsi muscle were divided but the distal border wasn't dissected. After a 2 to 3 weeks vascular delay period, the muscle was stimulated with a sequential protocol method for 8 weeks. Biopsy samples of the bilateral LDM were taken 8 weeks later. The conditioned muscle was compared with its unconditioned contralateral control by ATPase stain with both alkine and acid preincubation and electromicroscopic changes. At the end of 8 weeks condition, a 98. 8 ± 1. 9% transformation was demonstrated in group one, 97. 7± 2.5% in group two. Mitochondrial density increased and myofibrillae revealed narrow and branched in the transformed muscular cells.To compare the physical characteristics between the conditioned and unconditioned skeletal muscle, bilateral LDM of the 7 dogs as above were freed. The...