The Diagnosis Based On Overall Analysis Of Epigastralgia Of Traditional Chinese Medicine And The Gastroscope And The Relevant Experimental Index

Objective: To approach the diagnosis based on overall analysis of epigastralgia of traditional Chinese medicine and the relevant experimental index.Methods:1. Investigation of literature: general study and statistics analysis on epigastralgia-related literature and essays to keep abreast of the change of the name, pathogenesis, diagnostic pattern and the progress of study for the determination of more unified diagnostic pattern and its relation with relevant experimental index.2. Clinical epidemiological study: through retrospective study on the 900 cases with chief complaint of epigastralgia in upper alimentary tract in Nanchang to approach the diagnosis and pattern, and the chief symptoms with statistic significance for diagnosis.3. to study the interrelationship of the syndromes through the measurement and analysis of HP infection, content of gastric mucosa inhibition change, the functional gastrotestinel disorder, the function of motilin and gastric acid. Results:1. investigation of literature: Through general study on the ancient and present literature, we found that our forefathers did the research on the epigastralgia early in history. However, they mixed up "cardiac pain" and "stomachache", which leads to disagreement on epigastralgia in later ages. Doctors in Jin and Yuan Dynasties used it as an independent name, the diagnosis and treatment was progressively improved in Ming and Qing Dynasties. The patters were in disagreement, mostly based on clinical reports and personal experience. The patterns and approaches have guiding significance in clinical and scientific research. But the objectivity of diagnosis was neglected. The investigation of literature can be classified as wei qi yong zhi, gan wei qi zhi, wei zhong yun re, gan wei yun re, yu xue zhu zhi, wei yin bu zhu, pi wei xu han, much the same as the classification in relevant textbooks.2. Epidemiological study: according to the results of clustering analysis, the symptoms can be divided into 7 syndromes. According to the results of multi-logistic analysis and principal components analysis, we know that there are chief symptoms with statistic significance in diagnosing a syndrome pattern, with the study of differentiation of symptoms and signs of epigastralgia.3. The result of experiment: The patients with epigastralgia is more likely to have HP infection than the normal control group. The secretion of gastric antrum mucosa growth inhibition is significantly more in the cases with sthenia-syndrome than in the cases with asthenia-syndrome and the control group. The gastrin secretion has much to do with the movement of stomach. The change of quantity of the secretion of gastric acid has direct influence on the digestion and absorption of food.Conclusion:1. The investigation of literature, especially the general study of ancient and modern literature, is one of the important tasks and approaches in the scientific research of traditional Chinese medicine.2. The retrospective approach to the clinical epidemiological study has certain scientific significance in standardizing research of syndromes of traditional Chinese medicine.3. Clustering analysis, multi logistic analysis and principal components analysis are helpful in the differentiation of symptoms and signs of epigastralgia.4. Modern experimental approaches are helpful for the acknowledgment of the nature of the syndrome.