Design, Synthesis And Properties Development Of The Chemosensors Based On Pyrrole Bridged System

We designed and synthesized two family of chemosensors and developed their recognition properties in this work. The two family of chemosensors were:(1) 2,3-bis(1H-pyrrol-2-yl)quinoxaline-functionalized hydrazones; (2)β-functionalized porphyrins.Novel 2,3-bis(1H-pyrrol-2-yl)quinoxaline-functionalized hydrazones were prepared and characterized as new chemosensors for metal ions. The binding properties of them for metal ions (Co2+, Ni2+, Cu2+, Zn+) were examined by UV-vis, fluorescence spectroscopy, and linear sweep voltammetric experiments (LSV). The selective and sensitive recognition properties towards Cu2+of the chemosensors were exhibited in not only spectroscopy changes, but also in the solution color changes which can be observed by the naked eye. The results suggested that our findings will help to improve the direct detection of Cu2+ ion in the environment.On the other hand, adopting the rarely usedβ-functionalization strategy in porphyrin-based sensor design, another binding site was appended onto the metalloporphyrin molecular framework affording some ditopic chemosensors. The assembled chemosensor interacts selectively with some guests via a "two-point" binding mode. The binding properties of them for guests were examined by UV-vis, fluorescence spectroscopy, HR-MS, and1H NMR, and found the chemosensors exhibited selective recognition properties towards some biological bifunctional guests respectively.