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The Study Of Systematic Reviews Of Treatment Of Discussion Of Treatise On Cold-Induced And Miscellaneous Diseases On Diabetes â…¡ And Its Complications

Posted on:2014-01-17Degree:DoctorType:Dissertation
Country:ChinaCandidate:J J ChenFull Text:PDF
GTID:1224330398963261Subject:TCM clinical basis
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ObjectiveDiabetes and its Complications is very common chronic disease in Hong Kong, about700,000Hong Kong people suffering from it, this number is still increasing, and condition in China is more serious.No meter the past or now, theTreatment of Discussion of Treatise on Cold-Induced and Miscellaneous Diseases on Diabetes II and its complications is also good, but we still don’t have a systematic study on it. In this thesis, we aim to use systematic review and evident base study together with the experience of those masters, to study the efficacy of theTreatment of Discussion of Treatise on Cold-Induced and Miscellaneous Diseases on Diabetes Ⅱ and its complications and summarize, investigate its recipe, treatment law, in order to guide the future clinical or research theTreatment of Discussion of Treatise on Cold-Induced and Miscellaneous Diseases on Diabetes II and its complications.MethodsRevMan5.2will be used as the assessment of the efficacy, as OR or RR95%CI. Microsoft Office Excel is used as the study of calculation of syndrome type, treatment law and the prescriptions.By using different keyword such as the formula name, books name and diseases name, searching on the database:CNKI. Then1. Deleting repeated literature.2. Dividing the Literature is into two group diabetes II and diabetes complications.3. Select the literature have controlled clinical study for the systematic review.4. Combining and investigating the result of systematic review.ResultsX19527result is get in the first search, by reading the title and abstract collection1762. According to the inclusion and exclusion criteria were collected58:including Type2diabetes [16], diabetic peripheral neuropathy (5), diabetic foot (3), diabetic gastroparesis [14], diabetes, neurogenic bladder lesions (3), diabetic nephropathy [13], diabetes, cerebral infarction(3), diabetes hyperlipidemia (2).Treatment of type2diabetes, the treatment group was significantly improved to54.22%,34.12%in the control group.16literature there is no significant heterogeneity (RR)0.2confidence interval0.16-0.24, P<0.05, statistically there is a very significant meaning.The big bupleurum in the treatment the type2diabetes, treatment group was significantly improved to54.54%in the control group was18.05%. Literature there is no significant heterogeneity (RR)0.37confidence interval0.23-0.52, P<0.05, statistically there is a very significant meaning.Jinkuishenqiwan the treatment of type2diabetes treatment group was significantly improved to51.14%, and31.76%in the control group. Literature there is no significant heterogeneity.(RR)0.19confidence interval0.12-0.27, and P<0.05, statistically there is a very significant meaning.Treatment of type2diabetes and peripheral neuropathy treatment group was significantly improved to55.30%,24.11%in the control group. Literature there is no significant heterogeneity (OR)3.97confidence interval2.70-5.84, P<0.05, statistically there is a very significant meaning.Treatment of type II diabetic foot treatment group was significantly improved to41.67%,28.43%in the control group. Literature there is no significant heterogeneity (OR)1.89confidence interval1.04-3.41, and P <0.05, statistically there is a very significant meaning.Treatment of type2diabetic gastroparesis treatment group was significantly improved to51.63%,31.03%in the control group.(OR)2.48confidence interval1.91-3.21, P<0.05, statistically there is a very significant meaning.Treatment of type2diabetes and peripheral neuropathy treatment group was significantly improved to42.86%,23.91%in the control group. Literature can be combined.(OR)3.11confidence interval1.22-7.93, P<0.05, statistically there is a very significant meaning.Treatment of type2diabetic nephropathy peripheral neuropathy treatment group was significantly improved for41,86%of the control group was20.22%. Literature there is no significant heterogeneity (OR)3.07confidence interval2.32-4.05, P<0.05, statistically there is a very significant meaningTreatment of type2diabetes and peripheral neuropathy treatment group was significantly improved to76.77%,49.77%in the control group. Literature there is no significant heterogeneity (OR)3.33confidence interval2.19-5.05, P<0.05, statistically there is a very significant meaning.The treatment of type2diabetes and high cholesterol lesions and Western medicine Comparison of efficacy of the treatment group was40.00%,26.53%in the control group. After statistics, the two literature there is no significant heterogeneity (OR)1.58confidence interval0.85-2.95, and P<0.05, statistically there is a very significant meaning.The six most common symptom type of diabetes II:1. Deficiency of Qi, deficiency of Yin3. heat4. Stasis, spleen6. Inefficiency of qi, deficiency of kidney. Six most commonly used Therapeutic law:1. Eradicates stasis, Reinforcing Yin, Reinforcing yang, clear the heat, reinforcing qi, and Reinforcing kidney. The most commonly used prescription:1. Shen Qi Wan2. large Chai Hu soup3BHT.Type2diabetic peripheral neuropathy three most common symdrome type: stasis, Deficiency of yin, Deficiency ofyang. The three most commonly used treatment Law:clear the stasis, reinforcing qi, reinforceing yang and clear cold, the two most commonly used prescription:Astragalus Gui Zhi Wu Wu the soup, Dangguisini soup.The two most common syndrome type of the type2diabetic foot:stasis, heat, the most commonly used Therapeutic law:warming yang and, clear heat, clear the stasis reinforcing kidney, reinforcing qi, reinforcing yin, the most commonly used prescription:Jingguishenqi pillType Ⅱ diabetes gastroparesis most common syndrome:mixed cold and heat or each knot,yin deficiency, spleen and stomach,phlegm drink. The most commonly used Therapeutic law:built spleen and stomach, phlegm wet drink, Qi, Jiangni flat stomach. The most commonly used prescription:BanxiaxiexinTang, wheat Asp soup.Type Ⅱ diabetes neurogenic bladder disease research is not a particularly outstanding syndrome type the literature into a smaller number.The three most common syndrome type of type2diabetic nephropathy:yin, yang, kidney. The three most commonly used TreatmentLaw:eradicates wet phlegm, expel stasis, warming yang and. The three most commonly used prescription:Jingguishenqi pill, Wulingsan, Zhen Wu Tang.Type2diabetes and cerebral infarction is a common finding cure the two most common syndromes:stasis, yin deficiency. The four most commonly used Treatment Law:expel stasis, qi, yang, Yin Zi. Most commonly used the prescription:Jinkuishenqitang soup.Type2diabetes and hyperlipidemia Therapeutic law heat, phlegm, reinforcing kidney, spleen adjustment, warming yang and, Yin. Most common syndrome type spleen disease.ConelusionXThe results show that, classical prescriptions the treatment of diabetes and complications than Western.Diabetes late emergence of blood stasis, inefficient of qi is more common in recent years, pathogenesis, and inefficient of qi different stages Individually appear. The Early Diabetes visible heat syndrome, the late kidney deficiency syndrome is more common.The diabetes Therapeutic law more common in the late circulation drugs, adjusting qi or liver qi stagnation can improve part of the traditional three-consumer poor efficacy of the treatment of patients.Type2diabetic peripheral neuropathy stasis-oriented, and the blood circulation throughout the entire process, such as the most common treatment method is qi lawType Ⅱ diabetic foot bleeding throughout the whole of this disease, the deficiency of this disease is also common, but due to blood stasis with positive imaginary proportion of different, the amount is also different. Warming Yang is also the most used treatment method.Type2diabetic gastroparesis Pinellia eradicates wet goods, common in all the evidence the main square or subtraction drugs, of which to Pinellia Xiexin soup the most multi-purpose. Built the General Law of the spleen and stomach of the disease, but also help to treatment method. Eradicates stasis method applied in this disease compared to other complication, but after a long illness into each other.Type Ⅱ diabetes neurogenic bladder lesions with the experiment of the control classical prescriptions the treatment of this disease is still insufficient. Type2diabetic nephropathy, a serious condition than complex, multi-syndrome and folders, evil is real positive imaginary cross, but based on syndrome-based virtual type, evil is real syndrome-based type is relatively small, but positive virtual shall see the real evil, real evil shall see the positive imaginary. Virtual syndrome type, mainly in the kidney, stasis symptoms of the disease has been throughout the entire process.Problems of this thesis1. Part of the literature of complications insufficient, due to the insufficient clinical studies of present classical prescriptions treatment with the control group2. Part of the literature on the etiology and pathogenesis or Therapeutic law or sub-type or prescription records are incomplete or ambiguous record.3. Most of the literature, addition and subtraction drugs with the card becomes even more than the main square with the drug.In this thesis, the problems found indicating future research directions, the following is the outlook for the future clinical papers:1. Increase classical prescriptions the main prescriptions, a controlled clinical study, so the future research and analysis can be more convincing.2. Documented etiology and pathogenesis, classification, medication should be more systematic and clear.3. To minimize changes in the main prescriptions after subtraction drug, to ensure that the square of specificity.4. Control study should be set during the studying of classical prescriptions.
Keywords/Search Tags:Diabetes, Complication, Systematic system, meta analysis
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