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The Relationship Between Climatic Parameters And Air Pollutants On Emerency Room Visits For Asthma

Posted on:2015-09-13Degree:DoctorType:Dissertation
Country:ChinaCandidate:W H DiFull Text:PDF
GTID:1224330467960859Subject:Emergency department
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Background Asthma is a common inflammatory disease of acute onset of chronicrespiratory mainly wheezing, coughing, chest tightness and difficulty breathing. Studieshave shown that rapid changes in the external environmental factors can easily lead toacute attacks of asthma.Object By integrating emergency clinical data and meteorological data, analyzeclimatic factors (temperature, pressure and relative humidity) and air pollutants (ozone,nitrogen dioxide, sulfur dioxide, PM10, etc.) on emerency room visits, and for the furtherdiscussion of the environment and human health, relationships provide some basis.Methods Asthma emergency department in our hospital during the period of2008-2013as the primary case study and classification: the first group to date emerencyroom visits, including emergency hospital admissions in the year, season, month, weekand day as a unit; first II by age groups, including zero-infant group15to14years old-64years old adult groups, more than65years of age or older, regardless of age group andthe group; third category on the basis of the second category is further sub-grouping of themale group, female group. First, the characteristics of emergency department patientswith onset time for descriptive statistics, and six years of emergency data and air pollutionmonitoring stations and meteorological stations in the same period of the data binding forPearson correlation analysis and multiple regression analysis. And by the case-controlstudy of patients with asthma were different methods of pollution levels and urban centersin rural areas, suburbs sampling, to explore the possible differences in the level ofasthma-related markersResults After statistical analysis of the results showed that: For pediatric patients withasthma, the asthma-prone in November, adult asthma-prone in December, elderlyasthma-prone in February. Sunday and Monday is the weekly emergency medical timethe top two most common, especially in children most obvious. For each sex, age group,patients with asthma, the various environmental factors associated with the incidence ofmonthly average data were greater than the average daily between data. Each gender, agegroup of patients with asthma were positively correlated with nitrogen dioxide andatmospheric pressure, and the temperature, absolute humidity has a negative correlation. Monthly mean data, the impact of the maximum temperature on the total number ofemergency the most obvious, the coefficient of determination R2is49.2%; highestpressure emergency hospital admissions for asthma in children affected most obviousdetermination coefficient R2of37%; highest influence of temperature on the number ofemergency medical treatment of adult patients with asthma most obvious determinationcoefficient R2was42.9%, the lowest temperature and absolute humidity on the numberof emergency medical geriatric most obvious, the coefficient of determination R2was28.7%.Experimental results show that both the air polluted areas or non-air-polluted areas,asthmatics eosinophilic cationic protein (ECP), interleukin-5(IL-5), tumor necrosisfactor (TNF-α) and IgE were significantly than in healthy people, and a statisticallysignificant; platelet counts were also significantly higher than in healthy people, andmean platelet volume (MPV) was significantly lower than in healthy people, and werestatistically significant. Analysis of the number of asthma patients under different airquality of life of the display, each of the above areas with serious air pollution molecularlevel (city center) life of patients with asthma is higher than the non-serious air pollutionareas (suburban rural) life.Conclusion For Emergency medical treatment for patients with asthma, the impact ofweather changes more evident than changes in air pollution concentrations, when poor airquality, will not necessarily result in a high incidence of asthma, but if the weatherconditions at this time are high-pressure, low-temperature impact, it will cause anincrease in the number of emergency. Conversely, even if the concentration did notexceed air pollution standards, in cold weather, the air pressure is high, low absolutehumidity and relative humidity is high, the next day the temperature difference is notlikely to cause atmospheric pop asthma Emergency medical treatment visits, especiallyfor children. Air pollution may be the treatment of asthma disease severity in patientswith Emergency medical treatment have a certain influence. The reason may not onlybecause some of the dust particles in air pollutants induce the occurrence or aggravationof asthma, and some allergens present in polluted air may be the cause of air pollution inthe region of asthma exacerbations.
Keywords/Search Tags:Asthma, Emerency room visits, Climatic factors, particulates matter
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