| ObjectivesThis dissertation was performed to discuss the research progress and application status of evidence-based dentistry in the field of prosthodontics. Methodology and technology of evidence-based dentistry would be required and appraised to guide the practice of evidence-based prosthodontics.MethodsIn this dissertation, an electronic systematic literature search was conducted in MEDLINE (PubMed), EmBase, Cochrane Library and in combination with other Chinese databases (Chinese Biomedical Medical Database, China National Knowledge Infrastructure, Wan Fang Date and VIP Database) from April,2014 to March,2016. The aim was to establish a systematic view of the methodology and technology of evidence-based dentistry as well as to discuss the research progress and application status of evidence-based prosthodontics practice. On the one hand, systematic reviews and meta-analysis could be synthesized from controlled clinical trials or cohort studies to address clinical issues. Practitioners would become more proficient at being "doers"of evidence-based dentistry during those processes. On the other hand, it was difficult and eventually untenable for a full-time clinician to capture the findings reported in each study as the number of them increased. If readers could focus on question formulation and matching those questions to the various evidence resources, then they would be best "users" of evidence-based dentistry. Six cases and current available evidences would be reported in the following section, which including:Case one--the application of Michigan splint for bruxer after restoration treatment in maxillary anterior teethCase two-implant restoration for a single missing tooth in the anterior maxillaCase three--natural gingival profile creation and esthetic fixed restoration of missing maxillary anterior teeth due to tooth decayCase four--fixed prosthetic rehabilitation of a patient with severe tooth decayCase five--fixed prosthetic rehabilitation of a patient with severe periodontitisCase six--management of partially edentulous patient by providing removable partial dentures.ResultsSystematic review and meta-analysis from controlled clinical trials was synthesized to evaluate the efficacy of desensitizing agents, potassium nitrate and sodium fluoride, for tooth bleaching treatments. Potassium nitrate and sodium fluoride reduced tooth sensitivity while no consistent conclusion in changing tooth color was found. Another meta-analysis based on cohort studies was performed to evaluate the relationship between bruxism and dental implant failure. In contrast to non-bruxers, prostheses in bruxers had a higher failure rate.Through the practicing of evidence-based dentistry, clinicians had achieved better understanding of oral diseases, such as bruxism, tooth decay and periodontitis. Meanwhile, it also had a positive promation of learning in prosthetic rehabilitation, esthetic restoration and partially edentulous management.ConclusionsThe focus of the dissertation was to complete the summary of evidence resources through evidence-based dentistry and evidence-based dental practice learning. Moreover, the quality of case reporting, quantity of knowledge updating and efficiency of clinical issue solving had been improved by applying best evidence to clinical practing. |