The Research On The Syndrome Distribution Regularity Of Gastroesophagesl Reflux Disease And Exploring Pattern Differentiation Of TCM In Singapore

Objective:To investigate the epidemiological survey of Singapore by retrospective case analysis,to summarize the syndromes and syndromes of gastro esophageal reflux disease,and to find out the related factors of symptoms and symptoms to explore the etiology and pathogenesis.And the evolution of the course of the disease for the clinical treatment of traditional Chinese medicine to provide a reference.Through the collection of clinical data to observe the effectiveness of traditional Chinese medicine syndrome differentiation and treatment of gastro esophageal reflux disease and adverse reactions to study the clinical thinking of Chinese medicine,to explore the standardization of Singapore patients and individualized treatment.Methods:505 cases of gastro esophageal reflux disease were collected,according to the TCM four diagnostic information syndrome classification database,the use of SPSS statistical method to summarize the syndrome of gastro esophageal reflux disease syndromes,and its analysis with a variety of factors the correlation between.Analysis results used in clinical treatment of 44 patients,selected patients have been treated for more than 3 months main symptoms of RDQ and TCM syndrome points,oral Chinese medicine particles for 8 weeks 1day14-16g,2 times a day,the observation points were 2 weeks,6 weeks,8weeks,after the completion of 8 weeks of treatment,before treatment and after their own comparison,the control statistics to evaluate the efficacy.By SPSS 20 statistical software for processing,after t test,P<0.01 that the difference was statistically significant.Treatment after 8 weeks of withdrawal in one month and 3 months follow up 'observed long—term efficacy.Results:the age of the study to 50-69 years of age for the most,the course of disease in 1 year up to the incidence of factors to diet factors,emotional factors,drug factors are the most common,the top 10 symptoms,including acid reflux Gas,upper abdominal fullness,pharyngeal symptoms,dry mouth,heartburn posterior sterna pain,stomach noisy,upper abdominal burning,mouth bitter,common margin of the tongue with pale pink and white coating,common pulse is wiry pulse or thread plulse.Card type ratio of Liver and stomach heat>Disharmony between the liver and stomach>Weak in the spleen and stomach with reflux>Accumulation of phlegm and dampness>Yin deficiency stomach heat>Live qi stagnation and blood stagnation.The multivariate stepwise logistic regression analysis:course of the disease,vomiting,etc are the main related factors for Disharmony between the liver and stomach.Gender,emotional factors,heartburn,recurrent oral ulcer are the main related factor for Liver and stomach heat.Course of the disease,drug,heartburn,chronic cough are the main related factor for Weak in the spleen and stomach with reflux.Gender,emotional,heartburn,chronic cough pharyngeal symptoms are the main related factor for Accumulation of phlegm and dampness.Altogether 44 patients from TCM gastroenterology in Singapore,cases were ineffective 4cases(9.09%),18 cases(40.91%),were effective,21 cases(47.73%)were effective,and 0 coses(0%)were curative effect,the total effective rate was 90.91%.For the symptoms of heartburn,acid reflux,posterior sterna pain,stomach contents rushed to RDQ questionnaire(tolerance table)for symptom score calculation,after treatment decreased significantly,atypical reflux symptoms and other systemic symptoms of TCM Syndrome Points,after treatment also decreased significantly,the difference was statistically significant(P1<0.01),before treatment was P>0.05,the difference was not statistically significant.After the withdrawal of long-term efficacy of observation,symptom score less than 50%before treatment,or RDQ scale questionnaire and got 12 points were recurrent,in 44 cases,withdrawal in 1 month recurrence of 3 Case,after 3 months of recurrence 8 cases,11 cases.the recurrence rate was 27.50%,no recurrence of 72.50%,long-term effect is ideal.Conclusion:gastro esophageal reflux disease to stomach loss of decline,spleen lost ascending air lift disorders as the main pathogenesis,involving the organs and spleen and stomach,liver and gallbladder,lung-related,and the live is most closely.Pathological factors to qi stagnation,heat,phlegm,blood stasis as the standard,the first disease and more to gas-based,more common evidence,long illness spleen and stomach deficiency,in the virtual gas against the disease,due to virtual reality The pathology of the actual situation.Clinical syndrome differentiation treatment,syndrome differentiation and disease combination,good curative effect,long-term is ideal,is suitable for the treatment of Singapore patients.