| Hydrogels are a kind of polymer with three-dimensional hydrophilic polymeric networks.Based on the amphiphilicity,biocompatibility and flexibility,the hydrogels have been widely studied in material science and biological science.However,due to the poor mechanical properties and simple functionalization,the applications of hydrogels are limited,especially in the field of biomaterials and flexible wearable electronic devices.In this work,combining the environmental stimuli-response,molecular recognition,drug controlled release,conductivity and hydrogels,the multi-functional hydrogels are designed and synthesized,and the applications in biomedical materials and flexible wearable energy storage are studied.A brief summary of results is as follow:(1)A series of Poly(2-methoxyethyl acrylate-poly(ethylene glycol)methyl ether acrylate-acrylic acid)hydrogels were prepared.The PMA hydrogels had controllable thermal/pH dual-responsive and good mechanical properties.Following the content of acroleic acid,the PMA hydrogels had excellent selective absorption properties for the organic cationic dye with fast adsorption rate and maximum adsorption capacity(0.488 mg/mg),compared with the reported adsorption materials.Though the pH,the release of PMA could be controlled.PMA had a broad application prospect in the field of pollution treatment and controllable drug release.(2)A novel amphiphilic hyperbranched copolymer Hyperbranched Polymers Boltorn H20-Phenol-Styrene-Epichlorohydrin(H20-PSE)was prepared.The amphiphilic polymer could form micelles by self-assembling in aqueous solution with bright fluorescence and temperature/oxidation-reduction stimuli-response.Though the temperature,the release from H20-PSE could be controlled.Combining the H20-PSE with PMA,the composite hydrogels weres prepared and showed good steps-release.This complex drug carrier provided a new way to study the controlled release of multiple drugs.(3)The surface moleculary imprinted polymer magnetic cellulose microspheres(MIP-MCM)was prepared with Artesunate as template molecule.It not only solved the problems of irregular shape,unstable binding sites,deep embedding and difficult elution,but also had the magnetic response,imaging ability and pH stimuli-response ability,compared with the traditional imprinted polymers.The MIP-MCM had excellent specific adsorption performance for Artesunate with fast adsorption rate and maximum adsorption capacity.Though adjusting pH,the release of MIP-MCM could be controlled.MIP-MCM had a broad application prospect in the field of drug separation,purification and controlled release.(4)A hydrogel with self-healing and solubility was prepared by sodium alginate/poly-methacrylic acid(SAMA).Besides the good swelling and water-soluble ability,the SAMA hydrogel also had a good self-healing ability.The SAMA hydrogel as wound dressing showed excellent dissolution and release properties,which had a wide application prospect in the field of hemostatic dressing,wound dressing and surgical sealant.(5)A hydrogel with adsorption property was prepared by sodium alginate/poly(acrylamide-co-acrylicacid)(SAA).Based on the carboxyl binding sites,the SAA hydrogles had an excellent adsorption ability for Li~+with fast adsorption rate and maximum adsorption capacity.The maximum adsorption amount was 0.171g/g.Besides that,the adsorbed SAA@Li hydrogel had good electrochemical property.Hence,the SAA hydrogels not only could be used as adsorbent material for Li~+,but also could be used as gel electrolyte.(6)Based on the results of(5),A series of conductive hydrogels were prepared by sodiu alginate/poly(acrylamide-co-acrylicacid)/NaCl(SAM).The SAM hydrogels not only had good mechanical and electrochemical properties,but also had temperature stimuli-response.The resistance of SAM hydrogels could be adjusted through temperature changing.Based on these characteristics,the SAM hydrogels had a wide range of applications in the fields of flexible wearable electronics,safe ion batteries,sensors and biological devices. |
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