Study On Preparation And Properties Of Multifunctional Medical Cotton Fabric

Cotton fabric is one of the commonly used fabrics in the textile field at present,but single-function cotton fabric has been difficult to meet people’s pursuit of high-quality life.Some small molecular groups,polymers,nanoparticles and other substances are chemically grafted on the surface of cotton fabric is an effective method to prepare multiple functions of cotton fabrics.In addition to compounds with functional groups,the application of nanotechnology is getting more and more attention.Nano materials have many unique advantages in antibacterial applications,which make them show great potential.First of all,nano materials can be precisely controlled in size,surface chemistry,shape,etc.;they can be made into functional materials with internal antibacterial activity through cell membrane damage or nutritional deficiency,light assisted antibacterial and immune regulation,etc.Secondly,nanomaterials as drug delivery carriers can promote the permeability,controlled release and targeted bacterial absorption of natural or synthetic polymers,improve their bacteriostatic stability,and the efficacy rate with reduced dose.More importantly,nanomaterials can be designed to have a variety of broad-spectrum bactericidal functions to reduce the chance of bacterial resistance.In addition,it is of great significance to develop advanced antibacterial textile materials by nanomaterials.Based on this paper,the research work mainly includes the following aspects:In this study,the surface of nano titanium dioxidewith double bond was modified and Ag nanoparticles were deposited on the surface of the modified nano titanium dioxide.The antibacterial nano particles（Ag@M-Ti O₂）were graftedonto cotton fabric.The results show that the modified cotton fabric has high-efficiency and long-lasting antibacterial function.Even after 50 times of washing,the antibacterial rate against Staphylococcus aureus and Escherichia coli can still be maintained at more than 90%.The affinity of the modified cotton fabric to blood is enhanced.When the modified cotton fabric contacts with blood,the blood can spread rapidly on the surface of the cotton fabric and be absorbed.It was found that the hemostatic effect of the modified cotton fabric could be significantly improved by testing and characterizing the internal bleeding model of the liver.At the same time,because of the excellent bactericidal effect of the modified cotton fabric,it can effectively kill the bacteria in the wound and promote the rapid healing of the wound.In addition,the adhesion of bacteria to cotton fabric was also studied.Although the cotton fabric treated with Ag@M-Ti O₂NPs has a highly effective bactericidal function,the modified cotton fabric lacks a certain high-efficiency function of preventing bacterial adhesion.A large number of bacteria can still propagate rapidly on the surface of the cotton fabric,forming plaque or biofilm,thus causing the fabric to turn yellow,producing peculiar smell and even reducing the original mechanical properties of the cotton fabric,even the bactreia killed by the modified cotton fabric will still adhere to the surface of cotton fabric,which will affect the increase of added value of cotton fabric.Based on this,in the next work,using nanoparticles in Ag@M-Ti O₂as a crosslinking agent,zwitterionic compound 3-[N,N-two methyl-[2-（2-methyl propylenoxy）ethyl]ammonium]propane-1-sulfonic acid internal salt（SBMA）,hydroxyethyl methacrylate（HEMA）were used as comonomer,and were prepared a nanoparticles hybridized zwitterionic hydrogel.Adopting organosilicon quaternary ammonium salt antimicrobial agents as coupling agents,and the hydrogel particles were grafted onto cotton fabrics.The obtained cotton fabric not only has an effective antibacterial effect,but also can effectively resist the adhesion and proliferation of bacteria on the cotton fabric Moreover,the antibacterial effect of cotton fabric is more durable and stable due to the addition of organosilicon antibacterial agent.After 50 times of washing,the antibacterial experiment of cotton fabric shows that it still meets the requirements of AAA class antibacterial textiles.In addition,the pore structure of hydrogels,the anti protein adsorption function of hydrogels,the biocompatibility of hydrogels,and the antibacterial properties of hydrogels have been studied in detail in this work.Although the antibacterial effect of nano silver particles is remarkable,excessive use will cause irreversible damage to the water environment and ecological balance.For environmental protection consideration,a non-toxic and environmentally friendly cationic antibacterial nanoparticle was prepared.This nanogel is composed of styrene（St）,polycaprolactone,hydroxyethyl methacrylate（PCL-HEMA）,polyhexadiene guanidine hydrochloride（M-PHGC）.The obtained nanogels had regular spherical morphology with an average particle size of 200 nm.Because nanogels are polymerized by hydrophilic macromonomers and hydrophobic monomers in aqueous solution,the hydrophilic antibacterial macromolecular segments are mostly distributed on the surface of nano hydrogels,which makes nanogels more excellent bactericidal effects.In addition,the anti infection wound model experiment confirmed that the nanogels had the ability to prevent infection.Moreover,after the nanogels was grafted on the surface of cotton fibers by chemical bonding,the efficient hydrophobic and antibacterial properties of cotton fabrics could effectively prevent bacteria from adhering on cotton fabrics.The excellent thermal stability,excellent biocompatibility and contact non bactericidal ability make the nano hydrogel exhibit excellent potential in durable and environmentally friendly nano antibacterial.Using cationic antibacterial agent to finish cotton fabric can make cotton fabric have excellent antibacterial performance.However,after cleaning with anionic detergent for many times,the antibacterial function of cotton fabric will be gradually inactivated.Therefore,we designed a finishing scheme based on the synergistic antibacterial action of cationic and haloamines.The cotton fabric can killed bacteria by contact and release pathways,due to the strong electrostatic adsorption effect of cationic compounds,close contacting between bacteria and the surface of cotton fabric makes the antibacterial performance of haloamines on cotton fabric fully play.The antibacterial test results show that the antibacterial effect of cotton fabric against Staphylococcus aureus and Escherichia coli can still be maintained at 99.9%,even after 50 times of washing with anionic detergent.More importantly,this modification method has little effect on the original wearing performance of cotton fabric.