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A novel equation to assess degree of crystallinity of filament yarns and hyaluronic acid nanofiber wound dressing and electrospinning of cellulose nanofibers

Posted on:2006-09-16Degree:Ph.DType:Dissertation
University:Kansas State UniversityCandidate:Uppal, RohitFull Text:PDF
GTID:1451390008465804Subject:Textile Technology
Abstract/Summary:
An equation was developed to predict degree of crystallinity of aramid filament yarns using dissolution time (DT) data of Kevlar and Nomex mutifilament yarns, which were heat-set at various temperatures. The coefficient of correlation between DTinv and the X-ray degree of crystallinity was found to be -0.39 for nylon multifilament yarns.; Biopolymers, especially bioactive materials, are becoming more popular for several medical applications like artificial hips, artificial heart valves, artificial joints, and scaffolds that heal and promote growth of tissues. Scaffolds made up of poly (L-lactic acid) or glycolic acid or collagens are a few (Behanna et al., 2005). Enzymes may be incorporated into the biopolymer nanofibers so as to make them bioactive. These bioactive nanofibers can promote various biological functions, such as secretion of insulin by the pancreas, angiogenesis or cell proliferation etc. Hyaluronic acid (HA) is one such bioactive material, which aids in cellular repair, heals wounds faster as it helps in mitosis of epithelial cells, cell migration, cell proliferation, and angiogenesis. Hence, it was postulated that hyaluronic acid would be a perfect material for making a nanofiber wound dressing. Based on the analysis of the photographs taken by a digital camera and the pathological report, it was concluded that the healing of the wounds was the best in case of HA nanofiber wound dressing followed by antibiotic dressing, vaseline gauze, solid hyaluronic acid, and adhesive bandage. The effects of polymer flow rate, spin length, and the applied voltage on the average diameter of the hyaluronic acid nanofibers was studied. The thickness and the air permeability of hyaluronic acid nanofiber dressing were measured. The degree of crystallinity of hyaluronic acid nanofibers was 20.6%.; Cellulose was elcetrospun into nanofibers using N-methylmorpholine-N-oxide/N-methyl pyrrolidinone/water solvent mixture. Alpha-cellulose did not dissolve in sodium hydroxide/urea aqueous solutions. Alpha-cellulose solution in phosphoric acid was not electrospinnable. An attempt was made to filter out bacteria with the help of cellulose nanofibers web.
Keywords/Search Tags:Acid, Nanofibers, Nanofiber wound dressing, Degree, Crystallinity, Yarns, Cellulose
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