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A Bayesian approach to biokinetic models of internally-deposited radionuclides

Posted on:1998-03-31Degree:Ph.DType:Dissertation
University:The University of TennesseeCandidate:Amer, Mamun FFull Text:PDF
GTID:1460390014979524Subject:Nuclear engineering
Abstract/Summary:
ayesian methods were developed and applied to estimate parameters of biokinetic models of internally deposited radionuclides for the first time. Marginal posterior densities for the parameters, given the available data, were obtained and graphed. These densities contain all the information available about the parameters and fully describe their uncertainties. Two different numerical integration methods were employed to approximate the multi-dimensional integrals needed to obtain these densities and to verify our results. One numerical method was based on Gaussian quadrature. The other method was a lattice rule that was developed by Conroy. The lattice rule method is applied here for the first time in conjunction with Bayesian analysis. Computer codes were developed in Mathematica's own programming language to perform the integrals. Several biokinetic models were studied. The first model was a single power function, ;The second model was a single exponential function,...
Keywords/Search Tags:Biokinetic models, First
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