Kinetic isotope effects and hydrogen tunneling in the yeast triosephosphate isomerase reaction

Posted on:1996-08-24

Degree:Ph.D

Type:Dissertation

University:University of Arkansas

Candidate:Alston, William Curtis, II

Full Text:PDF

GTID:1461390014986593

Subject:Organic Chemistry

Abstract/Summary:

Secondary kinetic isotope effects were measured for the base-catalyzed proton exchange reaction of acetophenone in deuterium oxide at 25;The secondary deuterium kinetic isotope effects of the deuteroxide-ion catalyzed exchange of methyl protons of acetophenone in D;The secondary kinetic isotope effects for the yeast triosephosphate isomerase reaction are normal (KIE ;The secondary H/T and D/T kinetic isotope effects for the (1(Re)-...

Keywords/Search Tags:

Kinetic isotope effects, Triosephosphate isomerase reaction

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